Collins W E, Mertens H W, Higgins E A
Aviat Space Environ Med. 1987 Apr;58(4):328-32.
Each of 17 men was trained on 7 tasks in the Multiple Task Performance Battery and then performed over a 2-week period in four experimental sessions: ground level with and without alcohol, and simulated altitude (12,500 ft), with and without alcohol. Subjects breathed appropriate gas mixtures through oxygen masks at both ground level and altitude. Alcohol doses of 100-proof vodka mixed with juice 2.2 ml X kg-1 of body weight. Results showed no differential effect of simulated altitude on breathalyzer readings (peaks averaged 78 mg % at 12,500 ft and 77 mg % at ground level). The best performance occurred at ground level under placebo conditions; the 12,500-ft simulated altitude produced some decrement for placebo scores. Alcohol at ground level resulted in significantly impaired performance during the morning sessions; the addition of altitude to the alcohol condition further depressed performance scores, but to about the same extent that placebo scores were depressed by altitude. Thus, there was no synergistic interactive effect of alcohol and altitude on either breathalyzer readings or performance scores.
17名男性每人都在多任务表现测试组中接受了7项任务的训练，然后在为期2周的时间里进行了4次实验：在地面有酒精和无酒精的情况下，以及在模拟海拔（12500英尺）有酒精和无酒精的情况下。受试者在地面和海拔高度时都通过氧气面罩呼吸适当的混合气体。酒精剂量为将酒精度数为100的伏特加与果汁混合，每千克体重2.2毫升。结果显示，模拟海拔对呼气测醉器读数没有差异影响（在12500英尺处峰值平均为78毫克%，在地面为77毫克%）。在安慰剂条件下，最佳表现出现在地面；12500英尺的模拟海拔使安慰剂得分有所下降。地面饮酒导致上午时段的表现显著受损；在饮酒条件下增加海拔高度进一步压低了表现得分，但程度与海拔使安慰剂得分下降的程度大致相同。因此，酒精和海拔对呼气测醉器读数或表现得分均没有协同交互作用。
