Kronsten Victoria T, Gosson Caroline, Al-Khatib Alhamza, Bagwan Izhar, Worthington Tim, Muthalali Sneha, Ethell Mark, Lim Guan, Youd Philippa
Institute of Liver Studies, King's College Hospital NHS Trust, UK.
Gastroenterology Department, Epsom and St Helier University Hospitals NHS Trust, UK.
ACG Case Rep J. 2022 Jul 6;9(7):e00824. doi: 10.14309/crj.0000000000000824. eCollection 2022 Jul.
Enteropathy-associated T-cell lymphoma (EATL) is a rare but serious complication of celiac disease. Diagnosis is challenging. Patients can present with weight loss, abdominal pain, and diarrhea or acutely with bowel perforation or obstruction. Patients often present with advanced disease. Malnutrition further limits treatment options. Early diagnosis is important to start aggressive treatment strategies. However, even with prompt diagnosis, prognosis remains poor with a high mortality rate. We report the first documented case of sole tonsillar involvement, a rare extraintestinal and extranodal site of disease, leading to EATL diagnosis. We also highlight some of the challenges in diagnosing EATL.
肠病相关T细胞淋巴瘤（EATL）是乳糜泻一种罕见但严重的并发症。诊断具有挑战性。患者可能出现体重减轻、腹痛、腹泻，或急性出现肠穿孔或肠梗阻。患者常以疾病晚期就诊。营养不良进一步限制了治疗选择。早期诊断对于启动积极的治疗策略很重要。然而，即使及时诊断，预后仍然很差，死亡率很高。我们报告了首例有记录的仅累及扁桃体的病例，这是一种罕见的肠外和结外疾病部位，导致了EATL的诊断。我们还强调了EATL诊断中的一些挑战。
