Wang Zhihao, Guo Long, Li Jun, Li Jianji, Cui Luying, Dong Junsheng, Wang Heng
College of Veterinary Medicine, Yangzhou University, Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China.
Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education, Yangzhou, China.
Front Vet Sci. 2022 Jun 24;9:934081. doi: 10.3389/fvets.2022.934081. eCollection 2022.
A 5-year-old castrated male bulldog was diagnosed with a corneal ulcer accompanied by edema and conjunctival hyperemia. Ophthalmic examination and microbiological analysis were performed, and the bacteria were found to be gram-negative and globular. The isolated clone was identified as (MZ579539) MALDI-TOF MS and 16S rDNA sequencing. Antimicrobial susceptibility testing showed that the bacteria were sensitive to tetracycline and chloramphenicol, but resistant to levofloxacin and ciprofloxacin. After a conjunctival flap was placed, tobramycin ophthalmic solution and 5% sodium hyaluronate were administered. Following surgery, the ulcer was effectively controlled, and after 3 weeks, the cornea healed. This is the first case report of a canine corneal ulcer associated with , which should be considered when corneal ulceration or keratitis were suspected.
一只5岁去势雄性斗牛犬被诊断为角膜溃疡，伴有水肿和结膜充血。进行了眼科检查和微生物分析，发现细菌为革兰氏阴性且呈球状。通过基质辅助激光解吸电离飞行时间质谱（MALDI-TOF MS）和16S核糖体DNA（rDNA）测序鉴定出分离的克隆为（MZ579539）。药敏试验表明，该细菌对四环素和氯霉素敏感，但对左氧氟沙星和环丙沙星耐药。放置结膜瓣后，给予妥布霉素滴眼液和5%透明质酸钠。手术后，溃疡得到有效控制，3周后角膜愈合。这是首例与[具体细菌名称未给出]相关的犬角膜溃疡病例报告，当怀疑角膜溃疡或角膜炎时应予以考虑。
