Patil Smita, Rossi Rosanna, Jabrah Duaa, Doyle Karen
CÚRAM, SFI Research Centre for Medical Devices, National University of Ireland Galway, Galway, Ireland.
Department of Physiology, National University of Ireland Galway, Galway, Ireland.
Front Med Technol. 2022 Jun 24;4:748949. doi: 10.3389/fmedt.2022.748949. eCollection 2022.
Stroke is one of the leading causes of disability worldwide. Early diagnosis and treatment of stroke are important for better clinical outcome. Rapid and accurate diagnosis of stroke subtypes is critical. This review discusses the advantages and disadvantages of the current diagnostic and assessment techniques used in clinical practice, particularly for diagnosing acute ischemic stroke. Alternative techniques for rapid detection of stroke utilizing blood based biomarkers and novel portable devices employing imaging methods such as volumetric impedance phase-shift spectroscopy, microwave tomography and Doppler ultrasound are also discussed. Current therapeutic approaches for treating acute ischemic stroke using thrombolytic drugs and endovascular thrombectomy are discussed, with a focus on devices and approaches recently developed to treat large cranial vessel occlusions.
中风是全球致残的主要原因之一。中风的早期诊断和治疗对于改善临床结果很重要。快速准确地诊断中风亚型至关重要。本综述讨论了临床实践中当前使用的诊断和评估技术的优缺点，特别是用于诊断急性缺血性中风的技术。还讨论了利用基于血液的生物标志物快速检测中风的替代技术，以及采用体积阻抗相移光谱、微波断层扫描和多普勒超声等成像方法的新型便携式设备。讨论了使用溶栓药物和血管内血栓切除术治疗急性缺血性中风的当前治疗方法，重点是最近开发的用于治疗大脑血管闭塞的设备和方法。
