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埃塞俄比亚一家教学医院的尿道下裂修复的临床特征和手术结果。

Clinical Profiles and Surgical Outcome of Hypospadias Repair at a Teaching Hospital in Ethiopia.

机构信息

Pediatric surgery unit, Department of surgery, St. Paul's hospital millennium medical college, Addis Ababa, Ethiopia.

Department of surgery, St. Paul's hospital millennium medical college, Addis Ababa, Ethiopia.

出版信息

Ethiop J Health Sci. 2022 May;32(3):613-622. doi: 10.4314/ejhs.v32i3.18.

DOI:10.4314/ejhs.v32i3.18
PMID:35813675
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9214746/
Abstract

BACKGROUND

Hypospadias repair is one of the commonest and challenging surgery done in pediatric age groups. This study was conducted to assess clinical profiles and surgical outcomes of hypospadias repair.

METHODS

A retrospective analysis of pediatric hypospadias repairs at St. Paul's hospital millennium medical college from September 2015 to August 2019 was conducted.

RESULTS

A total of 277 patients with hypospadias repair were investigated. The mean age was 3.7+/- 3.5 years (Range, 0.5-14 years) and only one-third (98,35.4%%) of patients were operated on in the recommended age group (6-18 months). Anterior/distal hypospadias was the commonest (123,44.4%) variant identified. The majority (176,63.5%) had chordee and 105(37.9%) were severe forms. Tubularized incised plate repair was the major (164,59.2%) surgical technique employed followed by staged urethroplasty (61,22%). Post-operative complications occurred in 135(48.7%) patients and the commonest was urethrocutanous fistula (95,34.3%). No significant correlation was found between the occurrence of these complications and factors such as age at repair, the severity of hypospadias, presence of concomitant urogenital anomaly, type of procedure and duration of urinary diversion. However, the presence of severe chordee (AOR=3.09; 95%CI 1.21-7.54; p=0.013) was an independent factor found to be associated with postoperative complications on multivariate analysis.

CONCLUSION

Higher rate of complications following hypospadias repair was observed in our study. Our study also demonstrated no significant advantage of any repair technique in reducing operative complications. Extensive preoperative evaluation, proper operative plan and regular follow-up of such patients is paramount for a better outcome.

摘要

背景

尿道下裂修复是小儿外科中最常见和最具挑战性的手术之一。本研究旨在评估尿道下裂修复的临床特征和手术结果。

方法

对 2015 年 9 月至 2019 年 8 月在圣保罗医院千年医疗学院进行的小儿尿道下裂修复术进行回顾性分析。

结果

共调查了 277 例尿道下裂修复患者。平均年龄为 3.7+/-3.5 岁(范围,0.5-14 岁),只有三分之一(98,35.4%)的患者在推荐的年龄组(6-18 个月)进行手术。最常见的是前/远端尿道下裂(123,44.4%)。大多数(176,63.5%)有阴茎弯曲,105 例(37.9%)为严重型。管状切开板修复是主要的(164,59.2%)手术技术,其次是分期尿道成形术(61,22%)。135 例(48.7%)患者发生术后并发症,最常见的是尿道皮肤瘘(95,34.3%)。在多因素分析中,未发现这些并发症的发生与修复时的年龄、尿道下裂的严重程度、合并的泌尿生殖系统异常、手术类型和尿流改道持续时间等因素有显著相关性。然而,严重阴茎弯曲(OR=3.09;95%CI 1.21-7.54;p=0.013)是独立的危险因素。

结论

本研究观察到尿道下裂修复术后并发症发生率较高。本研究还表明,任何修复技术在减少手术并发症方面都没有明显优势。广泛的术前评估、适当的手术计划和对这类患者的定期随访对于获得更好的结果至关重要。

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本文引用的文献

1
Long-Term Complications of Hypospadias Repair: A Ten-Year Experience from Northern Zone of Tanzania.尿道下裂修复术的长期并发症:来自坦桑尼亚北部地区的十年经验
Res Rep Urol. 2020 Oct 12;12:463-469. doi: 10.2147/RRU.S270248. eCollection 2020.
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Common Practice of Hypospadias Management by Pediatric Urologists in Indonesia: A Multi-center Descriptive Study from Referral Hospitals.印度尼西亚儿科泌尿科医生治疗尿道下裂的常见做法:一项来自转诊医院的多中心描述性研究
Open Access Maced J Med Sci. 2019 Jul 14;7(14):2242-2245. doi: 10.3889/oamjms.2019.628. eCollection 2019 Jul 30.
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Hypospadias Repair in Ethiopia: A Five Year Review.埃塞俄比亚的尿道下裂修复:五年回顾
Ethiop J Health Sci. 2018 Nov;28(6):735-740. doi: 10.4314/ejhs.v28i6.8.
4
Hypospadias, all there is to know.尿道下裂,全知道。
Eur J Pediatr. 2017 Apr;176(4):435-441. doi: 10.1007/s00431-017-2864-5. Epub 2017 Feb 11.
5
Intermediate-Term Followup of Proximal Hypospadias Repair Reveals High Complication Rate.近端型尿道下裂修复的中期随访显示高并发症发生率。
J Urol. 2017 Mar;197(3 Pt 2):852-858. doi: 10.1016/j.juro.2016.11.054. Epub 2016 Nov 10.
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Complications of hypospadias surgery: Experience in a tertiary hospital of a developing country.尿道下裂手术的并发症:一个发展中国家三级医院的经验
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Should Surgery for Hypospadias Be Performed Before An Age of Consent?尿道下裂手术应在达到同意年龄之前进行吗?
J Sex Res. 2016 Oct;53(8):1047-1058. doi: 10.1080/00224499.2015.1066745. Epub 2015 Oct 19.
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Prevalence, repairs and complications of hypospadias: an Australian population-based study.尿道下裂的患病率、修复情况及并发症:一项基于澳大利亚人群的研究。
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Hypospadias repair: a single centre experience.尿道下裂修复术:单中心经验
Plast Surg Int. 2014;2014:453039. doi: 10.1155/2014/453039. Epub 2014 Jan 20.
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Failed hypospadias in paediatric patients.小儿患者的尿道下裂失败案例。
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