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基于新型非自治延迟SIR模型对中国由新冠病毒引起的散发性COVID-19疫情的长期预测

Long-term prediction of the sporadic COVID-19 epidemics induced by -virus in China based on a novel non-autonomous delayed SIR model.

作者信息

Pei Lijun, Hu Yanhong

机构信息

School of Mathematics and Statistics, Zhengzhou University, Zhengzhou, 450001 Henan People's Republic of China.

出版信息

Eur Phys J Spec Top. 2022;231(18-20):3649-3662. doi: 10.1140/epjs/s11734-022-00622-6. Epub 2022 Jul 4.

Abstract

With the outbreaks of the COVID-19 epidemics in several provinces of China, government takes prevention and control measures to contain the epidemics. It is more difficult to make the long-term prediction of the sporadic COVID-19 epidemics than widespread ones in that the former cannot obey the laws of the infectious disease well like the latter. In this paper, we make long-term predictions including end time and final size, peak and peak time of current confirmed cases and the number of accumulative removed cases of the sporadic COVID-19 epidemics in different regions of China by a novel non-autonomous delayed SIR compartment model (S-susceptible, I-infected, R-removed). The key contribution of this paper is that under the rigorous containments, we find transmission rate is approximately an exponential decreasing function with respect to time t, rather than a fixed constant. In addition, the removed rate is approximately a piecewise linear increasing function instead of a linear increasing function which is (at + b)heaviside (t-14). First, according to the few data in the early stage, i.e., roughly the first 7 days, issued by the National Health Commission of China and local Health Commissions, we can accurately estimate these parameters, i.e., transmission and removed rates of the model. Then, by them, we accurately predict the evolution of the COVID-19 there. On the basis of them to predict Category A of the sporadic COVID-19 epidemics since July 20th, 2021 in this summer. The results agree very well to the actual ones. It is also adopted to predict Category B the tour group epidemics since October 17th, 2021 and Category C other sporadic epidemics since October 27th, 2021. The results show that although our method is simple and the needed data are very few, the long-term prediction of the sporadic COVID-19 epidemics in China is quite effective. We can use this novel non-autonomous delayed SIR model to accurately predict its end time and final size, peak and peak time of current confirmed cases and the number of accumulative removed cases in China. This work can help governments and policy-makers make optimal prevention and control policies for all cities and provinces to contain the COVID-19 epidemics, and prepare well for the resumption of work, production and classes in advance to reduce the economic and social losses.

摘要

随着中国多个省份爆发新冠疫情,政府采取防控措施以遏制疫情。对散发性新冠疫情进行长期预测比对广泛传播的疫情更困难,因为前者不像后者那样能很好地遵循传染病规律。在本文中,我们通过一种新颖的非自治延迟SIR compartment模型(S-易感者,I-感染者,R-康复者)对中国不同地区散发性新冠疫情的结束时间、最终规模、当前确诊病例的峰值和峰值时间以及累计康复病例数进行长期预测。本文的关键贡献在于,在严格的防控措施下,我们发现传播率近似于关于时间t的指数递减函数,而非固定常数。此外,康复率近似于分段线性递增函数,而非线性递增函数(at + b)heaviside(t - 14)。首先,根据中国国家卫生健康委员会和地方卫生健康委员会发布的早期少量数据,即大致前7天的数据,我们可以准确估计这些参数,即模型的传播率和康复率。然后,据此我们准确预测了当地新冠疫情的演变情况。在此基础上对2021年夏季自7月20日起的散发性新冠疫情A类进行预测。结果与实际情况非常吻合。该方法还被用于预测自2021年10月17日起的B类旅游团疫情以及自2021年10月27日起的C类其他散发性疫情。结果表明,尽管我们的方法简单且所需数据极少,但对中国散发性新冠疫情的长期预测相当有效。我们可以使用这种新颖的非自治延迟SIR模型准确预测其在中国的结束时间、最终规模、当前确诊病例的峰值和峰值时间以及累计康复病例数。这项工作有助于政府和政策制定者为所有省市制定最优防控政策以遏制新冠疫情,并提前做好复工、复产和复课准备,以减少经济和社会损失。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3038/9252558/a8be865c92d4/11734_2022_622_Fig1_HTML.jpg

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