菊苣酸：天然存在、化学合成、生物合成及其生物活性作用

Chicoric Acid: Natural Occurrence, Chemical Synthesis, Biosynthesis, and Their Bioactive Effects.

作者信息

Yang Min, Wu Chao, Zhang Tianxi, Shi Lei, Li Jian, Liang Hongbao, Lv Xuzhen, Jing Fengtang, Qin Lu, Zhao Tianlun, Wang Chenxi, Liu Guangxu, Feng Shuai, Li Feng

机构信息

Teaching and Research Office of Chinese Medicines authentication, College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.

Department of Pharmaceutical Preparation Technology, Department of Pharmaceutical Engineering, Shandong Drug and Food Vocational College, Weihai, China.

出版信息

Front Chem. 2022 Jun 23;10:888673. doi: 10.3389/fchem.2022.888673. eCollection 2022.

Chicoric acid has been widely used in food, medicine, animal husbandry, and other commercial products because of its significant pharmacological activities. However, the shortage of chicoric acid limits its further development and utilization. Currently, (L.) Moench serves as the primary natural resource of chicoric acid, while other sources of it are poorly known. Extracting chicoric acid from plants is the most common approach. Meanwhile, chicoric acid levels vary in different plants as well as in the same plant from different areas and different medicinal parts, and different extraction methods. We comprehensively reviewed the information regarding the sources of chicoric acid from plant extracts, its chemical synthesis, biosynthesis, and bioactive effects.