生发中心相关原发性皮肤弥漫性大B细胞淋巴瘤，腿部型：一例缓解病例报告
Germinal Centre-Related Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type: Report of a Remission Case.
作者信息
Liu Fang, Qi Fei, Zhang Xiuying, Cao Mei, Peng Shiguang
机构信息
Department of Dermatology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People's Republic of China.
出版信息
Clin Cosmet Investig Dermatol. 2022 Jul 6;15:1265-1269. doi: 10.2147/CCID.S373937. eCollection 2022.
Primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LTs) is a rare and the most aggressive type of the cutaneous B-cell lymphoma with poor prognosis and low therapeutic response. It mostly affects elderly women, with a 5-year survival rate of 50% if not efficiently treated. We present a 28-year-old male patient with indolent PCDLBCL-LT who reached nearly 100% clearance after six rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) chemotherapy sessions.
原发性皮肤弥漫性大B细胞淋巴瘤，腿部型（PCDLBCL-LTs）是一种罕见且侵袭性最强的皮肤B细胞淋巴瘤，预后差，治疗反应低。它主要影响老年女性，若未得到有效治疗，5年生存率为50%。我们报告一名28岁患有惰性PCDLBCL-LT的男性患者，在接受6个周期的利妥昔单抗联合环磷酰胺、多柔比星、长春新碱和泼尼松（R-CHOP）化疗后，几乎达到了100%的清除率。
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