在维生素 D 缺乏的女性中，咖啡饮用量与血清 25-羟维生素 D、非高密度脂蛋白水平和 TC/HDL 比值的关系。
The association of coffee consumption rate with serum 25-hydroxyvitamin D, non-HDL levels, and TC/HDL ratio in females with vitamin D deficiency.
机构信息
Michael Sayegh Faculty of Pharmacy, Aqaba University of Technology, Aqaba, Jordan.
Department of Surgery, School of Medicine, Al-Balqa Applied University, Al-Salt, Jordan.
出版信息
Womens Health (Lond). 2022 Jan-Dec;18:17455057221112268. doi: 10.1177/17455057221112268.
OBJECTIVES
The purpose of this study was to evaluate the association of coffee consumption rate with serum 25-hydroxyvitamin D, non-high-density lipoprotein cholesterol levels, and total cholesterol to high-density lipoprotein cholesterol ratio in females with vitamin D deficiency.
METHODS
This retrospective cross-sectional study was carried out by studying the records of 270 Jordanian females aged 18-65 years with varying degrees of vitamin D deficiency. Following completion of the questionnaire regarding their anthropometric characteristics and coffee consumption rate during the preceding 3 months, the participants were required to provide blood samples for analysis to measure 25-hydroxyvitamin D and lipid profile levels including non-high-density lipoprotein cholesterol and total cholesterol to high-density lipoprotein cholesterol ratio.
RESULTS
The current study demonstrated that coffee consumption rate and vitamin D deficiency were significantly positively connected with the total cholesterol to high-density lipoprotein cholesterol ratio ( = .003) in women with vitamin D deficiency. In addition, vitamin D deficiency alone correlated positively with non-high-density lipoprotein cholesterol levels and the total cholesterol to high-density lipoprotein cholesterol ratio ( = .010) and ( = .002), respectively.
CONCLUSION
Higher coffee consumption rate among women with vitamin D deficiency significantly elevated total cholesterol to high-density lipoprotein cholesterol ratio that may increase woman's risk of hyperlipidemia.
目的
本研究旨在评估女性维生素 D 缺乏症患者中咖啡摄入量与血清 25-羟维生素 D、非高密度脂蛋白胆固醇水平和总胆固醇与高密度脂蛋白胆固醇比值的相关性。
方法
本回顾性横断面研究通过研究 270 名年龄在 18-65 岁之间、维生素 D 缺乏程度不同的约旦女性的记录进行。在完成关于他们在前 3 个月内的人体测量特征和咖啡摄入量的问卷后，要求参与者提供血液样本进行分析，以测量 25-羟维生素 D 和血脂谱水平，包括非高密度脂蛋白胆固醇和总胆固醇与高密度脂蛋白胆固醇比值。
结果
本研究表明，在维生素 D 缺乏的女性中，咖啡摄入量与维生素 D 缺乏与总胆固醇与高密度脂蛋白胆固醇比值呈显著正相关（ = .003）。此外，维生素 D 缺乏本身与非高密度脂蛋白胆固醇水平和总胆固醇与高密度脂蛋白胆固醇比值呈正相关（ = .010）和（ = .002）。
结论
维生素 D 缺乏的女性中较高的咖啡摄入量显著升高了总胆固醇与高密度脂蛋白胆固醇比值，这可能会增加女性患高脂血症的风险。
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