Department of Immunology & Microbiology, Scripps Research, La Jolla, CA 92037, USA.
Department of Immunology & Microbiology, Scripps Research, La Jolla, CA 92037, USA.
Cell Host Microbe. 2022 Jul 13;30(7):899-901. doi: 10.1016/j.chom.2022.06.009.
The pathogenicity of disease-associated microbes varies widely between individuals. In this issue of Cell Host & Microbe, Rice et al. demonstrate that interactions between intestinal commensals reciprocally modulate the host immune response to each microbe, ameliorating the inflammation caused by one and dampening antibody responses to the other.
疾病相关微生物的致病性在个体之间差异很大。在本期《细胞宿主与微生物》中,Rice 等人证明,肠道共生菌之间的相互作用可调节宿主对每种微生物的免疫反应,减轻一种微生物引起的炎症,并抑制对另一种微生物的抗体反应。