Qiu Zhenduo, Yu Xiaoxiao, Zhang Junyan, Xu Chengjian, Gao Mengyue, Cheng Yanhua, Zhu Meifang
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University. Shanghai, 201620, China.
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University. Shanghai, 201620, China.
Biomaterials. 2022 Aug;287:121666. doi: 10.1016/j.biomaterials.2022.121666. Epub 2022 Jul 4.
Environmental monitoring and personal protection are critical for preventing and for protecting human health during all infectious disease outbreaks (including COVID-19). Fluorescent probes combining sensing, imaging and therapy functions, could not only afford direct visualizing existence of biotargets and monitoring their dynamic information, but also provide therapeutic functions for killing various bacteria or viruses. Luminogens with aggregation-induced emission (AIE) could be well suited for above requirements because of their typical photophysical properties and therapeutic functions. Integration of these molecules with fibers or textiles is of great interest for developing flexible devices and wearable systems. In this review, we mainly focus on how fibers and AIEgens to be combined for health protection based on the latest advances in biosensing and bioprotection. We first discuss the construction of fibrous sensors for visualization of biomolecules. Next recent advances in therapeutic fabrics for individual protection are introduced. Finally, the current challenges and future opportunities for "AIE + Fiber" in sensing and therapeutic applications are presented.
在所有传染病爆发（包括新型冠状病毒肺炎）期间，环境监测和个人防护对于预防和保护人类健康至关重要。结合传感、成像和治疗功能的荧光探针，不仅能够直接可视化生物靶点的存在并监测其动态信息，还能提供杀灭各种细菌或病毒的治疗功能。具有聚集诱导发光（AIE）特性的发光剂由于其典型的光物理性质和治疗功能，非常适合上述要求。将这些分子与纤维或纺织品相结合，对于开发柔性器件和可穿戴系统具有重要意义。在这篇综述中，我们主要基于生物传感和生物防护方面的最新进展，重点探讨纤维与AIE发光剂如何结合以实现健康保护。我们首先讨论用于生物分子可视化的纤维传感器的构建。接下来介绍用于个人防护的治疗性织物的最新进展。最后，阐述了“AIE + 纤维”在传感和治疗应用中当前面临的挑战以及未来的机遇。
