Wu Xianglei, Liu Ying, Zhu Jiafang, Yu Wenxin, Lin Xiaoxi
Department of Laser and Aesthetic Medicine, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China.
Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Clin Cosmet Investig Dermatol. 2022 Jul 8;15:1293-1300. doi: 10.2147/CCID.S372409. eCollection 2022.
Infraorbital dark circles (IDC) are commonly consulted in aesthetic practice. There is not yet a multifactorial approach to facilitating their treatment.
To investigate the safety and efficacy of the microneedle fractional radiofrequency (MRF) system for the treatment of IDC.
A prospective, split-face, evaluator-blind clinical trial was conducted to study the change in the overall appearance, color, and wrinkles in 21 female patients with mixed type IDC before and after MFR treatment.
Both patients and independent evaluators found significant improvement on the global aesthetic scales after the MFR treatment, especially on periorbital wrinkles (p=0.031). Trends in decreased melanin density in the IDC area were found, but no statistical differences were established. No side effects were observed.
MFR is a safe and effective modality for improving mixed type IDC by correcting the structural factors.
眶下黑眼圈（IDC）是美容实践中常见的咨询问题。目前尚未有一种多因素方法来促进其治疗。
研究微针分数射频（MRF）系统治疗IDC的安全性和有效性。
进行了一项前瞻性、半脸、评估者盲法的临床试验，以研究21例混合型IDC女性患者在MFR治疗前后整体外观、颜色和皱纹的变化。
患者和独立评估者均发现MFR治疗后在整体美学量表上有显著改善，尤其是眶周皱纹（p=0.031）。发现IDC区域黑色素密度有降低趋势，但未建立统计学差异。未观察到副作用。
MFR是一种通过纠正结构因素来改善混合型IDC的安全有效的方法。
