Lu Bo, Liu Zhenteng, Kong Fanlin, An Hepeng, Hou Xueling, Fan Guofeng, Dong Wei
Department of Orthopaedics, Hebei Petrochina Central Hospital Langfang 065000, Hebei, China.
Am J Transl Res. 2022 Jun 15;14(6):4260-4277. eCollection 2022.
Osteoarthritis (OA), the most prevalent form of arthritis, which affects up to 15% of the adult population. The work presented in this paper focuses on the analysis of the publications on osteoimmunology of OA. The purpose of this paper is to provide inspiration for future research on osteoimmunology of OA.
We extracted all of the English publications relevant to osteoimmunology of OA published from 1991-2020 from the Web of Science. SPSS, GraphPad Prism, Citespace, and VOSviewer were utilized to collect and analyze the publication trends in osteoimmunology of OA.
We identified a total number of 1,004 publications with a total number of citations of 35,675 by October 31, 2020. Most publications came from China (26.8%). The United States ranked second, but its average number of citations and H index ranked best (10,130 citations and 55 H-index). Shandong University is the main center of institutional cooperation. Most papers related to osteoimmunology of OA were published in the journal of . In this field, TAK PP published the most papers (15), while Kotake, S's article was cited the most frequently (1,195). As presented in Figure 6, the 70 keywords, defined as terms that appeared more than 50 times in all papers, were classified into four clusters molecular research, human research, animal research and cell research. Research on cytokines and pathways is the new trend in Molecular research.
The current status and global trend of osteoimmunology of OA revealed by this study indicates that there is a strong possibility that the number of papers will increase in the coming year, and the research on cytokines as well as pathways would be the next hot topic.
骨关节炎（OA）是最常见的关节炎形式，影响着高达15%的成年人口。本文所呈现的工作聚焦于对OA骨免疫学相关出版物的分析。本文旨在为未来OA骨免疫学研究提供启发。
我们从科学网中提取了1991年至2020年发表的所有与OA骨免疫学相关的英文出版物。利用SPSS、GraphPad Prism、Citespace和VOSviewer来收集和分析OA骨免疫学的出版趋势。
截至2020年10月31日，我们共识别出1004篇出版物，总被引次数为35675次。大多数出版物来自中国（26.8%）。美国排名第二，但其平均被引次数和H指数排名最佳（10130次被引和55的H指数）。山东大学是机构合作的主要中心。大多数与OA骨免疫学相关的论文发表在《 》杂志上。在该领域，TAK PP发表的论文最多（15篇），而Kotake, S的文章被引用的频率最高（1195次）。如图6所示，70个关键词（定义为在所有论文中出现次数超过50次的术语）被分为四个聚类：分子研究、人体研究、动物研究和细胞研究。细胞因子和信号通路的研究是分子研究中的新趋势。
本研究揭示的OA骨免疫学的现状和全球趋势表明，来年论文数量很有可能增加，细胞因子以及信号通路的研究将成为下一个热点话题。
