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家长提供的照片可作为儿童霰粒肿的结果测量指标。

Parent-provided photographs as an outcome measure for childhood chalazia.

机构信息

Eye Care Associates Inc, Poland, Ohio.

Jaeb Center for Health Research, Tampa, Florida.

出版信息

J AAPOS. 2022 Apr;26(2):60.e1-60.e5. doi: 10.1016/j.jaapos.2021.11.012. Epub 2022 Mar 18.

Abstract

PURPOSE

To determine whether smartphone photographs of children's eyelids are reliable for diagnosing the presence of chalazia.

METHODS

In this prospective cross-sectional study, 60 participants, 7 months to 16.5 years of age, at four sites were enrolled; all participants had a chalazion measuring at least 2 mm on at least one eyelid based on an in-person clinical examination by a pediatric eye care professional. Smartphone photographs taken by the parent during the office visit were uploaded to the study website. A masked reader assessed each photograph for the presence or absence of chalazia; results were compared with the gold standard clinical examination results. Sensitivity and specificity for the presence of chalazion by eyelid were calculated.

RESULTS

Photographs were available for 240 eyelids; 85 had at least one chalazion and 155 were without a chalazion based on clinical examination. The masked reader correctly classified 68 of 85 eyelids with at least one chalazion and 151 of 155 eyelids without chalazia for a sensitivity of 80% (95% CI, 72%-86%) and a specificity of 97% (95% CI, 94%-99%). Sensitivity improved to 89% for chalazia 5 mm or larger and 94% when superficially located within the eyelid.

CONCLUSIONS

Parental smartphone photographs appear to be useful in assessing chalazia in children as an alternative to in-office follow-up examinations. These photographs may be a valuable outcome measure in future clinical trials of chalazia treatment, especially when assessing larger lesions.

摘要

目的

确定儿童眼睑的智能手机照片是否可用于诊断霰粒肿。

方法

在这项前瞻性横断面研究中,共有来自四个地点的 60 名 7 个月至 16.5 岁的参与者入组;所有参与者均经儿科眼科医生进行的现场临床检查确定至少一只眼睑存在至少 2 毫米的霰粒肿。家长在就诊期间拍摄的智能手机照片被上传到研究网站。一位盲法读者评估每张照片是否存在霰粒肿;将结果与金标准临床检查结果进行比较。计算了眼睑存在霰粒肿的敏感性和特异性。

结果

共有 240 只眼睑的照片可用;85 只眼睑至少有一只霰粒肿,155 只眼睑临床检查无霰粒肿。盲法读者正确分类了至少有一只霰粒肿的 85 只眼睑中的 68 只和无霰粒肿的 155 只眼睑中的 151 只,敏感性为 80%(95%CI,72%-86%),特异性为 97%(95%CI,94%-99%)。当霰粒肿为 5 毫米或更大且位于眼睑表面时,敏感性提高到 89%,当位于眼睑表面时,敏感性提高到 94%。

结论

家长的智能手机照片似乎可用于替代门诊随访检查,评估儿童的霰粒肿。这些照片可能是未来霰粒肿治疗临床试验的有价值的结局指标,尤其是在评估较大的病变时。

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