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缺血性中风患者血脂异常的患病率:来自巴基斯坦的单中心前瞻性研究。

Prevalence of Dyslipidemia in Ischemic Stroke Patients: A Single-Center Prospective Study From Pakistan.

作者信息

Khan Raja Sheraz Ullah, Nawaz Mehwish, Khan Sarfaraz, Raza Hassan Ali, Nazir Talha, Anwar Muhammad Saad, Nadeem Hafiz Muhammad Faisal, Rehman Zia Ur, Akram Amina

机构信息

Internal Medicine, Shalamar Hospital, Lahore, PAK.

Internal Medicine, Hayatabad Medical Complex, Peshawar, PAK.

出版信息

Cureus. 2022 Jun 12;14(6):e25880. doi: 10.7759/cureus.25880. eCollection 2022 Jun.

Abstract

Background  is a debilitating condition that adds morbidity to the patient and is an economic burden to society. Several modifiable risk factors can be identified and controlled, and dyslipidemia is one such under-diagnosed and least reported risk factor in Pakistan. We aimed to conduct this study to determine the frequency of dyslipidemia in ischemic stroke patients. Methodology We conducted a prospective cross-sectional study for seven months at Shalamar Hospital, Lahore, from November 2020 to May 2021. One hundred four patients were enrolled as per inclusion and exclusion criteria. After informed consent, a blood sample was taken from the patients and sent to a laboratory to determine dyslipidemia. Demographic details, history, and co-morbidities were also noted on a performa. All the collected data were analyzed in SPSS 20.0. Results The mean age was 53.09 ± 12.51 years. Of 104 patients, 60 (57.69%) were male, and 44 (42.31%) were females, with a male-to-female ratio of 1.4:1. The mean duration of disease in our study was 5.77 ± 3.33 hours. The mean BMI was 27.54 ± 3.03 kg/m2. In our study, the frequency of dyslipidemia in ischemic stroke patients was 39.42% (41 patients).  Conclusion This study concluded that dyslipidemia in ischemic stroke patients is very high in the Pakistani population. This highlighted the need to control this modifiable risk factor in the population. Strategic measures, including pharmacological therapy and diet modification, should be adopted, and awareness about the disease burden, control, and importance should be spread.

摘要

背景 是一种使人衰弱的病症,会增加患者的发病率,也是社会的经济负担。可以识别并控制几个可改变的风险因素,血脂异常就是巴基斯坦一种诊断不足且报告最少的风险因素。我们旨在开展这项研究以确定缺血性中风患者中血脂异常的发生率。方法 我们于2020年11月至2021年5月在拉合尔的沙勒玛医院进行了为期七个月的前瞻性横断面研究。根据纳入和排除标准招募了104名患者。在获得知情同意后,采集患者的血样并送至实验室以确定是否存在血脂异常。还在一份表格上记录了人口统计学细节、病史和合并症。所有收集的数据均在SPSS 20.0中进行分析。结果 平均年龄为53.09±12.51岁。104名患者中,60名(57.69%)为男性,44名(42.31%)为女性,男女比例为1.4:1。我们研究中疾病的平均持续时间为5.77±3.33小时。平均BMI为27.54±3.03kg/m²。在我们的研究中,缺血性中风患者中血脂异常的发生率为39.42%(41名患者)。结论 本研究得出结论,巴基斯坦人群中缺血性中风患者的血脂异常发生率很高。这突出表明有必要在人群中控制这一可改变的风险因素。应采取包括药物治疗和饮食调整在内的战略措施,并传播关于疾病负担、控制和重要性的认识。

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