Riley T V
J Clin Pathol. 1987 Apr;40(4):384-6. doi: 10.1136/jcp.40.4.384.
The production of heparinase by a wide range of anaerobic bacteria isolated from clinical specimens was investigated. None of the 29 strains of Bacteroides fragilis produced heparinase. Of 62 other Bacteroides tested, only two of four strains of B ovatus, two of three strains of B thetaiotaomicron, and two of four strains of B uniformis were heparinase producers. None of the 48 strains of fusobacteria or seven strains of Veillonella produced heparinase. The anaerobic cocci (19 peptococci and seven peptostreptococci) were also negative for heparinase production as were 46 Clostridium spp tested. It was concluded that heparinase production by anaerobic bacteria was unlikely to play a part in the regional thrombophlebitis that sometimes occurs in anaerobic infections.
对从临床标本中分离出的多种厌氧菌产生肝素酶的情况进行了研究。29株脆弱拟杆菌均未产生肝素酶。在测试的其他62株拟杆菌中,仅卵形拟杆菌4株中的2株、多形拟杆菌3株中的2株以及单形拟杆菌4株中的2株能产生肝素酶。48株梭杆菌和7株韦荣球菌均未产生肝素酶。厌氧球菌(19株消化球菌和7株消化链球菌)以及测试的46株梭菌属也均未产生肝素酶。得出的结论是,厌氧菌产生肝素酶不太可能在厌氧感染时有时发生的局部血栓性静脉炎中起作用。