Wang Liang, Pan Xiaoqi, Jiang Lishi, Chu Yu, Gao Song, Jiang Xingyue, Zhang Yuhui, Chen Yan, Luo Shajie, Peng Cheng
School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu, China.
Front Nutr. 2022 Jun 29;9:943911. doi: 10.3389/fnut.2022.943911. eCollection 2022.
Chlorogenic acid (CGA), also known as coffee tannic acid and 3-caffeoylquinic acid, is a water-soluble polyphenolic phenylacrylate compound produced by plants through the shikimic acid pathway during aerobic respiration. CGA is widely found in higher dicotyledonous plants, ferns, and many Chinese medicine plants, which enjoy the reputation of "plant gold." We have summarized the biological activities of CGA, which are mainly shown as anti-oxidant, liver and kidney protection, anti-bacterial, anti-tumor, regulation of glucose metabolism and lipid metabolism, anti-inflammatory, protection of the nervous system, and action on blood vessels. We further determined the main applications of CGA in the food industry, including food additives, food storage, food composition modification, food packaging materials, functional food materials, and prebiotics. With a view to the theoretical improvement of CGA, biological activity mechanism, and subsequent development and utilization provide reference and scientific basis.
绿原酸（CGA），又称咖啡单宁酸和3-咖啡酰奎尼酸，是植物在有氧呼吸过程中通过莽草酸途径产生的一种水溶性多酚苯丙烯酸酯化合物。绿原酸广泛存在于高等双子叶植物、蕨类植物和许多中药材中，享有“植物黄金”的美誉。我们总结了绿原酸的生物活性，主要表现为抗氧化、肝肾保护、抗菌、抗肿瘤、调节糖代谢和脂代谢、抗炎、保护神经系统以及对血管的作用。我们进一步确定了绿原酸在食品工业中的主要应用，包括食品添加剂、食品储存、食品成分改性、食品包装材料、功能性食品原料和益生元。以期为绿原酸的理论完善、生物活性机制以及后续的开发利用提供参考和科学依据。
