Department of Radiation Oncology, Head and Neck Oncology Program, Dana-Farber Cancer Institute/Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Head Neck. 2022 Nov;44(11):2579-2599. doi: 10.1002/hed.27142. Epub 2022 Jul 18.
Interventions for head/neck cancer (HNC) survivors may not address their cancer-related and general health needs.
Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guided this systematic review of studies from 2000 to 2021 of interventions targeting cancer survivors treated with curative-intent, using MEDLINE, Embase, Emcare, and PsycINFO. Interventions were categorized into domains of the Quality of Cancer Survivorship Care Framework to characterize the scope and quality of interventions.
We identified 28 studies for inclusion: 13 randomized and 15 non-randomized. Most targeted surveillance/management of physical effects (n = 24) including 13 that also targeted psychosocial effects. Four studies addressed prevention/surveillance for recurrence/new cancers, one addressed health promotion/disease prevention, and one addressed chronic medical conditions. Most studies (n = 27) had medium-high risk of bias.
There are few high-quality studies addressing HNC survivorship. Future rigorously designed studies should address broader areas of care, including chronic disease management and health promotion/disease prevention.
针对头颈部癌症（HNC）幸存者的干预措施可能无法满足他们与癌症相关的和一般的健康需求。
本系统评价遵循了系统评价和荟萃分析的首选报告项目（PRISMA），对 2000 年至 2021 年期间以接受根治性治疗的癌症幸存者为目标的干预措施进行了研究，使用了 MEDLINE、Embase、Emcare 和 PsycINFO。干预措施被归类为癌症幸存者护理质量框架的领域，以描述干预措施的范围和质量。
我们确定了 28 项研究纳入本研究：13 项随机和 15 项非随机研究。大多数研究针对身体影响的监测/管理（n=24），其中 13 项研究还针对心理社会影响。四项研究针对复发/新发癌症的预防/监测，一项研究针对健康促进/疾病预防，一项研究针对慢性疾病。大多数研究（n=27）的偏倚风险为中高度。
针对 HNC 幸存者的高质量研究较少。未来应设计严谨的研究来解决更广泛的护理领域，包括慢性疾病管理和健康促进/疾病预防。
