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提高头颈癌患者的生活质量:3D 电子内窥镜辅助手术与传统手术方法的比较分析

Enhancing quality of life in head and neck cancer patients: a comparative analysis of 3D exoscope-assisted surgery vs. traditional approaches.

作者信息

Marchi Filippo, Bellini Elisa, Ioppi Alessandro, Simoni Federica, Iandelli Andrea, Filauro Marta, Mora Francesco, Sampieri Claudio, Peretti Giorgio

机构信息

Unit of Otorhinolaryngology-Head and Neck Surgery, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genova, Genoa, Italy.

出版信息

Front Surg. 2024 Apr 16;11:1358500. doi: 10.3389/fsurg.2024.1358500. eCollection 2024.

Abstract

INTRODUCTION

The increasing population of survivors of head and neck carcinomas is becoming more conspicuous. Consequently, the pivotal role of quality of life, particularly elucidated through the assessment of dysphagia and dysphonia, is progressively influencing the decision-making process. The current study aims to assess whether VITOM 3D could offer a comparable post-treatment quality of life to traditional approaches for patients with laryngeal cancer and oro-hypopharyngeal cancer.

METHODS

A case series of laryngeal cancer and oro-hypopharyngeal cancer patients treated either with an exoscopic-assisted surgical setup and with conventional treatments (transoral microsurgery and radio-chemotherapy) at the Otolaryngology Unit of IRCCS San Martino Hospital, Genoa, is presented. The post-treatment quality of life of the two cohorts were compared through the administration of the University of Washington Quality of Life Questionnaire, Voiceik Handicap Index-10, M.D. Anderson Dysphagia Inventory were administrated to both cohorts of patients.

RESULTS

In the laryngeal cancer group, a total of 79 patients were included. Of these, 50.1% underwent transoral exoscope-assisted surgery, while 49.9% underwent primary transoral microscopic-assisted surgical approach. No significant differences were observed in terms of the University of Washington Quality of Life Questionnaire and Voice Handicap Index-10 between the two subgroups. Conversely, in the oro-hypopharyngeal cancer group, 43 patients were included. Of these, 37.2% underwent primary transoral exoscope-assisted surgery, while 62.8% received (chemo)radiotherapy. No notable differences were reported in terms of the University of Washington Quality of Life Questionnaire and M.D. Anderson Dysphagia Inventory between the transoral exoscope-assisted surgery and (chemo)radiotherapy subgroups.

CONCLUSIONS

Assessments of quality of life, conducted through the University of Washington Quality of Life Questionnaire questionnaire, dysphonia evaluations using the Voice Handicap Index-10, and dysphagia assessments employing the M.D. Anderson Dysphagia Inventory questionnaire, demonstrate analogous outcomes between conventional treatment modalities and transoral interventions utilizing the 3D exoscope.

摘要

引言

头颈癌幸存者数量的增加日益显著。因此,生活质量的关键作用,尤其是通过吞咽困难和发声困难评估所阐明的,正逐渐影响决策过程。本研究旨在评估VITOM 3D对于喉癌和口下咽癌患者而言,能否提供与传统方法相当的治疗后生活质量。

方法

呈现了在热那亚IRCCS圣马蒂诺医院耳鼻喉科接受内镜辅助手术设置及传统治疗(经口显微手术和放化疗)的一系列喉癌和口下咽癌患者病例。通过发放华盛顿大学生活质量问卷对两组患者的治疗后生活质量进行比较,同时向两组患者发放嗓音障碍指数-10和MD安德森吞咽困难量表。

结果

在喉癌组中,共纳入79例患者。其中,50.1%接受经口内镜辅助手术,而49.9%接受初次经口显微辅助手术方法。两个亚组在华盛顿大学生活质量问卷和嗓音障碍指数-10方面未观察到显著差异。相反,在口下咽癌组中,纳入43例患者。其中,37.2%接受初次经口内镜辅助手术,而62.8%接受(放)化疗。经口内镜辅助手术和(放)化疗亚组在华盛顿大学生活质量问卷和MD安德森吞咽困难量表方面未报告显著差异。

结论

通过华盛顿大学生活质量问卷进行的生活质量评估、使用嗓音障碍指数-10进行的发声困难评估以及采用MD安德森吞咽困难量表进行的吞咽困难评估表明,传统治疗方式与使用3D内镜的经口干预之间的结果相似。

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