Ghosh Tamoghna, Suri Tejas M, Jat Kana R, Gupta Aditya K, Bhatnagar Sushma, Tiwari Pawan, Mittal Saurabh, Mohan Anant
Department of Pulmonary, Critical Care and Sleep Medicine, All India Institute of Medical Sciences, New Delhi, India.
Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Lung India. 2022 Jul-Aug;39(4):343-347. doi: 10.4103/lungindia.lungindia_128_22.
We aimed to describe the clinical profile and risk factors for severe disease in adolescents hospitalised with coronavirus disease 2019 (COVID-19).
A retrospective analysis of an admitted cohort of COVID-19 patients was performed at a tertiary hospital in North India. Adolescents aged 12-18 years who were hospitalised during the first wave (March-December, 2020) and the second wave (March-June, 2021) were included. Data on the demographic details, clinical presentation, laboratory parameters, disease severity at admission, treatments received, and in-hospital outcomes were retrieved.
The study included 197 adolescents with a median [inter-quartile range (IQR)] age of 15 (13-17) years, of whom 117 (59.4%) were male. Among these, 170 (86.3%) were admitted during the first wave. Underlying co-morbidities were present in nine (4.6%) patients. A total of 60 (30.9%) patients were asymptomatic. In the severity grading, 148 (84.6%) had mild, 16 (9.1%) had moderate, and 11 (6.3%) had severe disease. Fever (14.9%) and cough (14.9%) were the most commonly encountered symptoms. The median (IQR) duration of hospital stay was 10 (8-13) days, and six (3.1%) patients died in the hospital.
Adolescents admitted with COVID-19 had predominantly asymptomatic or mild disease, and the mortality rate was 3.1%.
我们旨在描述2019年冠状病毒病（COVID-19）住院青少年的临床特征和重症危险因素。
在印度北部一家三级医院对一组COVID-19住院患者进行回顾性分析。纳入在第一波疫情期间（2020年3月至12月）和第二波疫情期间（2021年3月至6月）住院的12至18岁青少年。收集人口统计学细节、临床表现、实验室参数、入院时疾病严重程度、接受的治疗及院内结局等数据。
该研究纳入了197名青少年，年龄中位数[四分位间距（IQR）]为15（13 - 17）岁，其中117名（59.4%）为男性。其中，170名（86.3%）在第一波疫情期间入院。9名（4.6%）患者存在基础合并症。共有60名（30.9%）患者无症状。在严重程度分级中，148名（84.6%）为轻症，16名（9.1%）为中症，11名（6.3%）为重症。发热（14.9%）和咳嗽（14.9%）是最常见的症状。住院时间中位数（IQR）为10（8 - 13）天，6名（3.1%）患者在医院死亡。
COVID-19住院青少年主要为无症状或轻症疾病，死亡率为3.1%。
