Department of Family Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Takeda Vaccines, Inc., Cambridge, Massachusetts, USA.
J Pediatric Infect Dis Soc. 2022 Oct 25;11(10):463-466. doi: 10.1093/jpids/piac067.
We measured antibody binding to diverse norovirus virus-like particles over 12 months in 16 children. All had maternal antibodies at 2 months, with estimated lowest levels at 5 months of age. Antibody increases after 3 months suggested natural infections. This information could guide the timing of future norovirus vaccines.
我们在 16 名儿童中测量了 12 个月内针对多种诺如病毒样颗粒的抗体结合情况。所有儿童在 2 个月时均具有母体抗体,估计在 5 个月大时抗体水平最低。3 个月后抗体增加表明发生了自然感染。这些信息可以指导未来诺如病毒疫苗的接种时间。