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正念训练对焦虑和抑郁严重程度和损伤影响的潜在中介作用:一项随机对照试验。

The potential mediating role of anxiety sensitivity in the impact of mindfulness training on anxiety and depression severity and impairment: A randomized controlled trial.

机构信息

Beijing Key Laboratory of Behavior and Mental Health, School of Psychological and Cognitive Sciences, Peking University, Beijing, China.

Faculty of Psychology, Beijing Normal University, Beijing, China.

出版信息

Scand J Psychol. 2023 Feb;64(1):21-29. doi: 10.1111/sjop.12860. Epub 2022 Jul 19.

DOI:10.1111/sjop.12860
PMID:35851956
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9839484/
Abstract

The benefits of mindfulness-based interventions to alleviate anxiety and depression have been supported by many studies. Given the effectiveness of mindfulness-based interventions on anxiety and depression, the underlying mechanisms need to be explored. Using a randomized waitlist-controlled design, this study investigated whether anxiety sensitivity was a potential mechanism for the impact of mindfulness training on anxiety and depression. Participants with high psychological distress were randomly assigned to an eight-week mindfulness intervention (N = 35) or a wait-list control group (N = 34). Before and after the intervention or corresponding waitlist period, participants completed measures of anxiety and depression severity and impairment and anxiety sensitivity. Separate mixed ANOVA demonstrated significant group (intervention vs. control group) × time (pre- vs. post-test) interactions for anxiety sensitivity and overall anxiety severity and impairment and marginally significant interaction for overall depression severity and impairment. Moreover, simple mediation models showed that reductions of anxiety sensitivity from pre- to post-test mediated the impact of mindfulness training on changes in anxiety and depression severity and impairment. The findings suggest that anxiety sensitivity is a potential mechanism underlying the effect of mindfulness training on anxiety and depression, which provides a new perspective for the study of processes of change of mindfulness-based interventions.

摘要

基于正念的干预措施缓解焦虑和抑郁的益处已得到许多研究的支持。鉴于基于正念的干预措施对焦虑和抑郁的有效性,需要探索其潜在机制。本研究采用随机等待期对照设计,探讨焦虑敏感性是否是正念训练对焦虑和抑郁影响的潜在机制。具有较高心理困扰的参与者被随机分配到为期八周的正念干预组(N=35)或等待名单对照组(N=34)。在干预或相应等待期前后,参与者完成了焦虑和抑郁严重程度和障碍以及焦虑敏感性的测量。单独的混合方差分析表明,焦虑敏感性的组间(干预组与对照组)×时间(前测与后测)交互作用在焦虑敏感性和整体焦虑严重程度和障碍以及整体抑郁严重程度和障碍方面具有统计学意义,在整体抑郁严重程度和障碍方面具有边缘统计学意义。此外,简单的中介模型表明,从前测到后测的焦虑敏感性降低中介了正念训练对焦虑和抑郁严重程度和障碍变化的影响。研究结果表明,焦虑敏感性是正念训练对焦虑和抑郁影响的潜在机制,为正念干预过程变化的研究提供了新的视角。

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