Penicipurate A, a new polyketide derivative from the endophytic fungus .

A new polyketide derivative containing a 3-hydroxydecanoic acid ester moiety, penicipurate A (), was purified from the solid cultures of the fungus , a fungal strain endophytic in the leaves of . The structure of was established by spectroscopic methods, including UV, IR, HRESIMS, 1D, and 2D NMR and C NMR chemical shifts calculations coupled with DP4+ analysis, as well as the chemical degradation method. Compound showed moderate inhibitory activity against pancreatic lipase (PL) with an IC value of 9.61 ± 1.42 µM.