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早期诊断,寿命更长?宫颈癌和乳腺癌筛查对寿命的影响。

Diagnose earlier, live longer? The impact of cervical and breast cancer screening on life span.

机构信息

Faculty of Humanities and Social Sciences, Macao Polytechnic University, Macao, People's Republic of China.

School of Public Administration, South China Agricultural University, Guangzhou, People's Republic of China.

出版信息

PLoS One. 2022 Jul 20;17(7):e0270347. doi: 10.1371/journal.pone.0270347. eCollection 2022.

Abstract

Cancer has become a leading cause of death and aroused the cancer scare. Breast and cervical cancer are two main health threats for women. In order to reduce mortality through early detection and early treatment, cancer screening has been widely recommended and applied for breast and cervical cancer detection and prevention. However, the benefit of cancer screening has been a controversial issue for the recent decades. The Chinese government has launched a free screening program on breast and cervical cancer for women since 2009. There is lack of strong data and sufficient information, however, to examine the effect of breast and cervical cancer screening. A Difference-in-Difference model estimated by Cox proportional hazard estimation was applied to evaluate the effects of breast and cervical cancer screening using data from Nown County Cancer Registry between the year 2009 and 2013. Based on the case study in a county of central China, this study found that the screening program reduced the risk of death, but found the lion's share for the benefit has been mainly due to the cervical cancer screening rather breast cancer screening, which may be related to the difference between early detection screening and preventive screening. Our results suggest sufficient funding and better education of related cancer knowledge will be meaningful measures for the prevention and treatment of breast and cervical cancer.

摘要

癌症已成为主要死因,引发了癌症恐慌。乳腺癌和宫颈癌是女性面临的两大主要健康威胁。为了通过早期发现和早期治疗降低死亡率,癌症筛查已被广泛推荐并应用于乳腺癌和宫颈癌的检测和预防。然而,近几十年来,癌症筛查的益处一直是一个有争议的问题。自 2009 年以来,中国政府为女性推出了免费的乳腺癌和宫颈癌筛查计划。但是,缺乏强有力的数据和充分的信息来检查乳腺癌和宫颈癌筛查的效果。本研究使用 Nown 县癌症登记处 2009 年至 2013 年的数据,应用 Cox 比例风险估计的差分模型来评估乳腺癌和宫颈癌筛查的效果。基于中国中部一个县的案例研究,本研究发现该筛查计划降低了死亡风险,但发现受益的主要原因是宫颈癌筛查而不是乳腺癌筛查,这可能与早期检测筛查和预防筛查之间的差异有关。我们的研究结果表明,充足的资金和更好的相关癌症知识教育将是预防和治疗乳腺癌和宫颈癌的有意义的措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71d6/9299384/b5859c1219dc/pone.0270347.g001.jpg

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