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肥胖老年患者行减重手术后的影响。

Impact of bariatric surgery in elderly patients with obesity.

机构信息

- Universidade Federal de Pernambuco, Pós-Graduação em Cirurgia - Recife - PE - Brasil.

- Universidade Federal de Pernambuco, Curso de Medicina - Recife - PE - Brasil.

出版信息

Rev Col Bras Cir. 2022 Jul 15;49:e20223299. doi: 10.1590/0100-6991e-20223299-en. eCollection 2022.

DOI:10.1590/0100-6991e-20223299-en
PMID:35858036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10578788/
Abstract

INTRODUCTION

to evaluate the long-term impact of bariatric surgery in the elderly population.

METHODS

a retrospective study including all patients older than 60 years who underwent Roux-en-Y gastric bypass (RYGB) at our center and maintained a follow-up longer than 1 year. Clinical and laboratory variables were studied to assess remission of obesity and its comorbidities, as well as variables directly related to the surgical procedure itself, including early and late complications.

RESULTS

fifty-six patients were studied, mostly female (76,8%), with a mean age of 64.02 ± 3.34. A rate of complications of 37,5% was observed, with 10,7% requiring hospital admission and emergency surgery. The mean excess weight loss (%EWL) was 74.22% ± 26.76. The remission rates of hypertension and diabetes mellitus were 26.08% and 54.54%, respectively. There was significant difference in BMI reduction (12.25 ± 5.42, p<0.001), total cholesterol (31.37 ± 38.89 p<0,001), LDL cholesterol (23.45 ± 34.9, p=0.002), HDL cholesterol (5.14 ± 11.13, p=0,024), triglycerides (48.85 ± 56.15 p<0.001), HbA1C (1,81 ± 1,97, p<0,001) e PCR (1.43 ± 1.96, p<0.001).

CONCLUSION

bariatric surgery was effective in weight loss and remission of comorbidities in the elderly obese population within the long term.

摘要

介绍

评估肥胖症手术在老年人群中的长期影响。

方法

一项回顾性研究,纳入在我院接受 Roux-en-Y 胃旁路手术(RYGB)且随访时间超过 1 年的所有 60 岁以上患者。研究了临床和实验室变量,以评估肥胖及其合并症的缓解情况,以及与手术本身直接相关的变量,包括早期和晚期并发症。

结果

共研究了 56 名患者,其中大多数为女性(76.8%),平均年龄为 64.02±3.34 岁。观察到 37.5%的并发症发生率,其中 10.7%需要住院和急诊手术。平均超重体重减轻率(%EWL)为 74.22%±26.76%。高血压和糖尿病的缓解率分别为 26.08%和 54.54%。体重指数(BMI)降低(12.25±5.42,p<0.001)、总胆固醇(31.37±38.89,p<0.001)、LDL 胆固醇(23.45±34.9,p=0.002)、高密度脂蛋白胆固醇(5.14±11.13,p=0.024)、甘油三酯(48.85±56.15,p<0.001)、糖化血红蛋白(HbA1C)(1.81±1.97,p<0.001)和 C 反应蛋白(PCR)(1.43±1.96,p<0.001)均有显著差异。

结论

肥胖症手术在长期内对老年肥胖人群的体重减轻和合并症缓解有效。

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本文引用的文献

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Obes Surg. 2021 Jun;31(6):2359-2363. doi: 10.1007/s11695-021-05316-x. Epub 2021 Mar 8.
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Bariatric surgery in the elderly: a randomized prospective study comparing safety of sleeve gastrectomy and Roux-en-Y gastric bypass (BASE Trial).老年患者的减重手术:一项比较袖状胃切除术和Roux-en-Y胃旁路术安全性的随机前瞻性研究(BASE试验)
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Comparative Safety and Effectiveness of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy in Obese Elder Patients: a Systematic Review and Meta-analysis.肥胖老年患者 Roux-en-Y 胃旁路术与袖状胃切除术的安全性和有效性比较:系统评价和荟萃分析。
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Laparoscopic Sleeve Gastrectomy Is Safe for Patients Over 60 Years of Age: A Meta-Analysis of Comparative Studies.腹腔镜袖状胃切除术对60岁以上患者是安全的:一项比较研究的荟萃分析
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Safety of bariatric surgery in patients older than 65 years.老年(65 岁以上)患者行减重手术的安全性。
Surg Obes Relat Dis. 2019 Aug;15(8):1380-1387. doi: 10.1016/j.soard.2019.05.016. Epub 2019 May 18.
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