Jamil Hashaam, Tariq Waleed, Tahir Muhammad Junaid, Mahfooz Rabia Salman, Asghar Muhammad Sohaib, Ahmed Ali
Lahore General Hospital, Lahore, 54000, Pakistan.
Shalamar Institute of Health Sciences, Lahore, Pakistan.
Ann Med Surg (Lond). 2022 Jun 23;79:104048. doi: 10.1016/j.amsu.2022.104048. eCollection 2022 Jul.
The recent monkeypox outbreak in non-endemic countries is a rare event. It is a zoonosis with clinical features similar to smallpox, transmitting from animal to human and human to human. Since 2000, the number of monkeypox cases in humans had increased in African countries, resulting in its spread to the other parts of the world. On May 26, 2022 World Health Organization has confirmed 120 cases of monkeypox in 23 non-endemic countries. The decreased immunity to the , human migration from endemic to non-endemic regions, genetic mutations in the viral genome, and reduced surveillance may contribute to the recent outbreaks. A multi-pronged approach comprising health education, tracking human migration, developing diagnostic facilities, and an effective vaccine could prevent transmission and pathogenicity.
近期在非流行国家爆发的猴痘疫情是一次罕见事件。它是一种人畜共患病，临床特征与天花相似，可从动物传播给人类以及在人与人之间传播。自2000年以来，非洲国家人类感染猴痘的病例数有所增加，导致其传播至世界其他地区。2022年5月26日，世界卫生组织已确认23个非流行国家有120例猴痘病例。免疫力下降、人类从流行地区向非流行地区迁移、病毒基因组中的基因突变以及监测力度减弱可能是近期疫情爆发的原因。包括健康教育、追踪人类迁移、发展诊断设施以及研发有效疫苗在内的多管齐下的方法可以预防传播和致病性。
