Genta R M, Weesner R, Douce R W, Huitger-O'Connor T, Walzer P D
JAMA. 1987 Jul 3;258(1):49-52.
The prevalence of strongyloidiasis among American veterans of the Vietnam and other wars was evaluated by testing several groups of veterans for serum IgG antibodies against Strongyloides stercoralis antigens, using an enzyme-linked immunosorbent assay. Of 493 Vietnam veterans, eight (1.6%) were seropositive. Of 60 patients with abdominal symptoms and/or elevated eosinophilia (greater than 0.08 [greater than 8%]) admitted to the Cincinnati Veterans Administration Medical Center, 12 (5%) were seropositive. Of 147 residents of a Veterans Administration-operated nursing home, six (4%) were seropositive. All infected patients in the latter two groups were World War II veterans. The usefulness of the enzyme-linked immunosorbent assay as a screening tool for at-risk groups is suggested by the finding that S stercoralis larvae were demonstrated in most seropositive patients when a sufficient number of fresh stools were examined.
通过酶联免疫吸附测定法检测几组退伍军人血清中抗粪类圆线虫抗原的IgG抗体，以评估越南战争及其他战争的美国退伍军人中类圆线虫病的患病率。在493名越南退伍军人中，8人（1.6%）血清呈阳性。在辛辛那提退伍军人管理局医疗中心收治的60例有腹部症状和/或嗜酸性粒细胞增多（大于0.08[大于8%]）的患者中，12人（5%）血清呈阳性。在一家退伍军人管理局运营的疗养院的147名居民中，6人（4%）血清呈阳性。后两组中的所有感染患者均为二战退伍军人。当检查足够数量的新鲜粪便时，在大多数血清阳性患者中发现了粪类圆线虫幼虫，这表明酶联免疫吸附测定法作为高危人群筛查工具的有效性。
