健康献血者中虫媒病毒的筛查：来自巴基斯坦卡拉奇的经验。
Screening for arboviruses in healthy blood donors: Experience from Karachi, Pakistan.
机构信息
Clinical Microbiology Laboratory, Department of Pathology & Lab Medicine, Aga Khan University, Karachi 74800, Pakistan.
Blood Bank, Haematology & Transfusion Medicine, Department of Pathology & Lab Medicine, Aga Khan University, Karachi 74800, Pakistan.
出版信息
Virol Sin. 2022 Oct;37(5):774-777. doi: 10.1016/j.virs.2022.07.008. Epub 2022 Jul 19.
• DENV, WNV and JEV status was investigated in healthy blood donors at the Aga Khan University July to December 2018. • ELISA for IgM antibodies and RT-PCR for viral RNA detection were performed. • IgM antibodies for DENV and WNV were positive in 3.9% and JEV in 0.28% of the blood donors. • Blood donors aged 19 and 30 years and residents of urban areas, of Karachi City were most frequent. • DENV and WNV seropositivity were significantly associated with residence in Malir District of Karachi.
• 2018 年 7 月至 12 月，在 Aga Khan 大学健康献血者中调查了登革热病毒（DENV）、西尼罗河病毒（WNV）和日本脑炎病毒（JEV）的情况。• 进行了 IgM 抗体酶联免疫吸附试验（ELISA）和病毒 RNA 检测的逆转录聚合酶链反应（RT-PCR）。• 在 3.9%的献血者中，DENV 和 WNV 的 IgM 抗体呈阳性，而 JEV 为 0.28%。• 年龄在 19 岁和 30 岁之间，居住在卡拉奇市的城市地区的献血者最为常见。• DENV 和 WNV 血清阳性与居住在卡拉奇市的 Malir 区显著相关。
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