Department of Clinical Laboratory, Guizhou Provincial People's Hospital, Guiyang, China.
J Int Med Res. 2024 Mar;52(3):3000605241236050. doi: 10.1177/03000605241236050.
Acute respiratory infections are a major global public health concern. However, there are few epidemiological studies investigating pathogens associated with respiratory tract infections in Guizhou Province, China.
We collected 17,850 blood samples from Guizhou Provincial People's Hospital between November 2018 and May 2023 to investigate the epidemiological characteristics of respiratory pathogens and their spread during the SARS-CoV-2 epidemic in Guizhou Province.
We identified influenza virus and as the predominant pathogens involved in acute respiratory infections in the study area. Immunoglobulin M positivity for respiratory syncytial virus, influenza virus, and showed a strong correlation with the clinical diagnosis of pneumonia. Seasonal epidemic patterns were observed for influenza A and B viruses. Following the SARS-CoV-2 outbreak, there was a significant decrease in the positive rates for most respiratory pathogens, particularly influenza A and B, , and respiratory syncytial virus.
This retrospective study contributes to the epidemiological evidence regarding respiratory pathogens in Guizhou Province, thereby enhancing the surveillance network for respiratory pathogens in China and providing valuable guidance for local hospitals.
急性呼吸道感染是一个重大的全球公共卫生关注点。然而，在中国贵州省，针对与呼吸道感染相关病原体的流行病学研究较少。
我们收集了贵州省人民医院在 2018 年 11 月至 2023 年 5 月间的 17850 份血样，以调查贵州省 SARS-CoV-2 疫情期间呼吸道病原体的流行病学特征及其传播情况。
我们发现流感病毒和 是研究区域急性呼吸道感染的主要病原体。呼吸道合胞病毒、流感病毒和 免疫球蛋白 M 的阳性与肺炎的临床诊断具有很强的相关性。流感 A 型和 B 型病毒呈季节性流行模式。SARS-CoV-2 疫情爆发后，大多数呼吸道病原体的阳性率显著下降，特别是流感 A 型和 B 型、 和呼吸道合胞病毒。
这项回顾性研究为贵州省呼吸道病原体的流行病学提供了证据，从而增强了中国呼吸道病原体监测网络，并为当地医院提供了有价值的指导。
