Liu Zhifeng, Guo Shaobo, Fang Xun, Shao Xianzhao, Zhao Zuoping
Shaanxi Key Laboratory of Catalysis, School of Chemical & Environment Science, Shaanxi University of Technology Hanzhong Shaanxi 723001 China
State Key Laboratory of Qinba Bio-Resource and Ecological Environment, Shaanxi University of Technology Hanzhong Shaanxi 723001 China.
RSC Adv. 2022 Jul 7;12(31):19856-19867. doi: 10.1039/d2ra03114k. eCollection 2022 Jul 6.
In this work, an FeO/Cu/CuO (FC) antibacterial nano-agent was synthesized in a "one-pot" approach using copper sulfate and ferric chloride as raw materials, and it was studied using TEM, XRD, XPS, UV-vis, and VSM methods. The antibacterial activity and mechanism of FC were studied, using a commercially available Bordeaux mixture as a control. The effects of an FC on mung bean development and its toxicity to human mammary epithelial cells were also investigated. The results revealed that FC could break the cell walls of and , quadrupling the antibacterial activity of the Bordeaux combination. Furthermore, it was shown that FC might improve the germination, root development, and chlorophyll content of mung bean seeds while being 1/8 as hazardous to human mammary epithelial cells as the Bordeaux combination. The as-prepared FC can replace the Bordeaux combination in the management of agroforestry pathogens.
在本研究中，以硫酸铜和氯化铁为原料，采用“一锅法”合成了FeO/Cu/CuO（FC）抗菌纳米剂，并通过透射电子显微镜（TEM）、X射线衍射（XRD）、X射线光电子能谱（XPS）、紫外可见光谱（UV-vis）和振动样品磁强计（VSM）等方法对其进行了研究。以市售波尔多液作为对照，研究了FC的抗菌活性及其作用机制。此外，还研究了FC对绿豆生长发育的影响及其对人乳腺上皮细胞的毒性。结果表明，FC能够破坏[具体细菌名称1]和[具体细菌名称2]的细胞壁，使波尔多液组合的抗菌活性提高四倍。此外，研究表明，FC可能会提高绿豆种子的发芽率、根系发育和叶绿素含量，同时对人乳腺上皮细胞的危害仅为波尔多液组合的1/8。所制备的FC可在农林业病原体管理中替代波尔多液组合。
