Kanaev S V, Gershanovich M L, Malinin A P, Kholin A V
Med Radiol (Mosk). 1987 May;32(5):16-21.
A total of 106 case histories of primary patients with stage III Hodgkin's disease aged 15 and older were analyzed. The treatment consisted of 2 introductory courses of polychemotherapy after MOPP scheme followed by a radical program of radiotherapy in 2-4 weeks, resulting in 88.7% of complete remissions. The 5-year survival rate was 81.3-6.3%, a 5-year recurrence-free course was noted in 83.8-5.2%. The 5-year survival rate was significantly lower in the patients with "unfavorable" histological types (mixed cellular and lymphoid depletion). A recurrence-free course over the same period was worse in men than in women, and in the patients with 5 and more zones of involvement.
对106例年龄在15岁及以上的Ⅲ期霍奇金病初治患者的病历进行了分析。治疗方案为在MOPP方案基础上进行2个周期的诱导多药化疗，随后在2 - 4周内进行根治性放疗，完全缓解率达88.7%。5年生存率为81.3 - 6.3%，5年无复发生存率为83.8 - 5.2%。组织学类型为“不良”（混合细胞型和淋巴细胞消减型）的患者5年生存率显著较低。同期男性的无复发生存情况比女性差，且受累区域为5个及以上的患者也是如此。
