Enzymes Inhibition and Antioxidant Potential of Medicinal Plants Growing in Oman.

The recent study was designed to explore , , , and using methanolic (MeOH) extract. Their subfractions were examined against urease, carbonic anhydrase II (CA-II), -glucosidase enzymes, and free radicals scavenging significance based on local practices via standard methods. Significance potential against the urease enzyme was presented by ethyl acetate fraction (EtOAc) of with ( = 125 ± 1.75 g/mL), whereas the ( = 146 ± 1.39 g/mL) in the EtOAc was found efficient to scavenge the free radicals. Besides, that appreciable capacity was observed by the , , , and as compared to the standard acarbose (IC = 377.24 ± 1.14 g/mL). Maximum significance was noticed in methanolic (MeOH) extract of and presented carbonic anhydrase CA-II (IC = 5.1 ± 0.20 g/mL) inhibition as compared to the standard (acetazolamide). We are reporting, for the first time, the CA-II inhibition of all the selected medicinal plants and -glucosidase, urease, and antioxidant activities of the . Thus, further screening is needed to isolate the promising bioactive ingredients which act as an alternative remedy to scavenge the free radicals, antiulcer, and act as a potential source to develop new antidiabetic drugs for controlling postprandial blood sugar as well as carbonic anhydrase inhibitors.