Mondal Shakti Chandra, Eun Jong-Bang
Department of Integrative Food, Bioscience and Biotechnology, Graduate School of Chonnam, National University, Gwangju, 61186 South Korea.
Department of Food Processing and Preservation, Hajee Mohammad Danesh Science and Technology University, Dinajpur, 5200 Bangladesh.
Food Sci Biotechnol. 2022 Apr 25;31(8):999-1008. doi: 10.1007/s10068-022-01091-2. eCollection 2022 Jul.
Diabetes mellitus (DM) type 2 is amongst the most common chronic diseases, being responsible for various problems in humans and contributing to increased mortality rates worldwide. Fructooligosaccharide, which can be produced from the roots of burdock ( L.), has been shown to have a wide range of pharmacological proprieties, including antiviral, anti-inflammatory, hypolipidemic, and antidiabetic effects. Moreover, burdock also contains chlorogenic acid, which has been used in traditional medicine as an antioxidant. Considering its natural origin and minimal toxicity, burdock fructooligosaccharides (BFO) has gained considerable attention from researchers owing its wide, efficient, and beneficial action against DM. Although the effectiveness of fructooligosaccharide and chlorogenic acid has been extensively discussed, limited information is available on the application of burdock for DM treatment. In this review, we discuss the beneficial contributions, and the recent in vitro and in vivo analytical findings on extract as DM therapy.
2型糖尿病（DM）是最常见的慢性病之一，它导致人类出现各种问题，并致使全球死亡率上升。从牛蒡（L.）根中提取的低聚果糖已被证明具有广泛的药理特性，包括抗病毒、抗炎、降血脂和抗糖尿病作用。此外，牛蒡还含有绿原酸，在传统医学中它被用作抗氧化剂。鉴于其天然来源和极低的毒性，牛蒡低聚果糖（BFO）因其对糖尿病广泛、高效且有益的作用而受到研究人员的广泛关注。尽管对低聚果糖和绿原酸的有效性已进行了广泛讨论，但关于牛蒡在糖尿病治疗中的应用信息有限。在本综述中，我们讨论了牛蒡提取物作为糖尿病治疗方法的有益贡献以及最近的体外和体内分析结果。
