Ydyrys Alibek, Zhamanbayeva Gulzhan, Zhaparkulova Nazgul, Aralbaeva Arailym, Askerbay Gulnaz, Kenzheyeva Zhanar, Tussupbekova Gulmira, Syraiyl Sayagul, Kaparbay Raushan, Murzakhmetova Maira
Biomedical Research Centre, Al-Farabi Kazakh National University, al-Farabi Av. 71, Almaty 050040, Kazakhstan.
Department of Biophysics, Biomedicine and Neuroscience, Al-Farabi Kazakh National University, al-Farabi Av. 71, Almaty 050040, Kazakhstan.
Plants (Basel). 2023 Dec 28;13(1):96. doi: 10.3390/plants13010096.
The objective of our research was to examine the antioxidant and membrane-protective characteristics of a few medicinal plant extracts belonging to the family, along with their flavonoid and polyphenolic content, in order to identify strategies for enhancing beverage composition and boosting the antioxidant capacity of green and black tea. The activity of aqueous-ethanolic extracts from the dried parts of plants, such as Mill., Kirp. & Kuprian. ex Kirp., Ledeb., Steph. ex Spreng., O.Berg, and L., were examined using a model of Wistar rats. Thiobarbituric acid-reacting substances (TBARS), a marker of malondialdehyde concentration, were used to measure the amount of lipid peroxidation (LPO) in liver microsomes. Considering the outcomes, the extracts from , , and exhibit the strongest membrane-stabilizing action among those examined. At a concentration of 5 g/mL, the extracts of these plants demonstrated a significant anti-hemolitic impact, whereas the remaining extracts displayed a similar effect at doses above 10 g/mL. Accordingly, among the extracts studied, the , , , , , and extracts have significant antioxidant properties. The integrated antioxidant and antihemolytic qualities of and green tea extracts were comparable to those of the individual plant extracts. When the extracts of and green tea were combined, similar outcomes were seen, suggesting that there was no appreciable synergistic interaction.
我们研究的目的是检测一些属于该科的药用植物提取物的抗氧化和膜保护特性,以及它们的黄酮类和多酚类含量,以便确定增强饮料成分和提高绿茶及红茶抗氧化能力的策略。使用Wistar大鼠模型检测了植物干燥部分(如Mill.、Kirp. & Kuprian. ex Kirp.、Ledeb.、Steph. ex Spreng.、O.Berg和L.)的水乙醇提取物的活性。丙二醛浓度的标志物硫代巴比妥酸反应物质(TBARS)用于测量肝微粒体中的脂质过氧化(LPO)量。考虑到结果,在所检测的提取物中,来自[具体植物1]、[具体植物2]和[具体植物3]的提取物表现出最强的膜稳定作用。在浓度为5 g/mL时,这些植物的提取物表现出显著的抗溶血作用,而其余提取物在剂量高于10 g/mL时表现出类似作用。因此,在所研究的提取物中,[具体植物4]、[具体植物5]、[具体植物6]、[具体植物7]、[具体植物8]和[具体植物9]的提取物具有显著的抗氧化特性。[具体植物10]提取物和绿茶提取物的综合抗氧化和抗溶血特性与单独的植物提取物相当。当[具体植物10]提取物和绿茶提取物混合时,观察到类似结果,表明没有明显的协同相互作用。