Bhanderi Shivam, Ain Quratul, Siddique Iram, Charalampakis Vasileios, Daskalakis Markos, Nijjar Rajwinder, Richardson Martin, Singhal Rishi
Department of General Surgery, Birmingham Heartlands Hospital, University Hospitals Birmingham NHS Foundation Trust, United Kingdom.
Clinic of General Surgery, Warwick Hospital South Warwickshire NHS Foundation Trust, Warwick, United Kingdom.
Turk J Surg. 2022 Mar 28;38(1):36-45. doi: 10.47717/turkjsurg.2022.5406. eCollection 2022 Mar.
Appendicectomy remains of the most common emergency operations in the United Kingdom. The exact etiologies of appendicitis remain unclear with only potential causes suggested in the literature. Social deprivation and ethnicity have both been demonstrated to influence outcomes following many operations. There are currently no studies evaluating their roles with regards to severity and outcomes following appendicectomy.
Demographic data were retrieved from health records for adult patients who underwent appendicectomy between 2010-2016 within a single NHS trust. To measure social deprivation, Indices of Multiple Deprivation (IMD) rankings were used. Histology reports were reviewed and diagnosis classified into predefined categories: non-inflamed appendix, uncomplicated appendicitis, complicated appendicitis and gangrenous appendicitis.
Three thousand four hundred and forty-four patients were identified. Mean age was 37.8 years (range 73 years). Using a generalized linear model, South Asian ethnicity specifically was found to be independently predictive of increased length of stay following appendicectomy (p <0.001). Amongst South Asian patients, social deprivation was found to be further predictive of longer hospital stay (p= 0.005). Deprivation was found to be a predictor of complicated appendicitis but not of gangrenous appendicitis (p= 0.01). Male gender and age were also independent predictors of positive histology for appendicitis (p <0.001 and p= 0.021 respectively).
This study is the first to report an independent association between South Asian ethnicity and increased length of stay for patients undergoing appendicectomy in a single NHS trust. The associations reported in this study may be a result of differences in the pathophysiology of acute appendicitis or represent inequalities in healthcare provision across ethnic and socioeconomic groups.
在英国,阑尾切除术仍是最常见的急诊手术之一。阑尾炎的确切病因尚不清楚,文献中仅提出了一些潜在原因。社会剥夺和种族均已被证明会影响许多手术后的结果。目前尚无研究评估它们在阑尾切除术后的严重程度和结果方面的作用。
从一个单一的国民保健服务信托机构中,检索2010年至2016年间接受阑尾切除术的成年患者的健康记录中的人口统计学数据。为衡量社会剥夺程度,使用了多重剥夺指数(IMD)排名。对组织学报告进行了审查,并将诊断分为预定义类别:非炎症性阑尾、单纯性阑尾炎、复杂性阑尾炎和坏疽性阑尾炎。
共识别出3444例患者。平均年龄为37.8岁(范围为73岁)。使用广义线性模型发现,南亚种族尤其可独立预测阑尾切除术后住院时间延长(p<0.001)。在南亚患者中,社会剥夺被发现可进一步预测住院时间延长(p=0.005)。剥夺被发现是复杂性阑尾炎的一个预测因素,但不是坏疽性阑尾炎的预测因素(p=0.01)。男性性别和年龄也是阑尾炎组织学阳性的独立预测因素(分别为p<0.001和p=0.021)。
本研究首次报告了在一个单一的国民保健服务信托机构中,南亚种族与接受阑尾切除术患者住院时间延长之间的独立关联。本研究报告的关联可能是急性阑尾炎病理生理学差异的结果,或代表了不同种族和社会经济群体在医疗保健提供方面的不平等。