Dong Yankai, Chen Shengquan, Wang Zhifei, Ma Yao, Chen Jinfeng, Li Ge, Zhou Jiahao, Ren Yating, Ma Hengyu, Xie Juanping, Li Hui, Zhu Zhongliang
Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Institute of Maternal and Infant Health, Northwest University, Xi'an, China.
Department of Neonatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Front Pediatr. 2022 Jul 6;10:846560. doi: 10.3389/fped.2022.846560. eCollection 2022.
Maternal stress during pregnancy can raise the risk of mental disorders in offspring. The continuous emergence of clinical concepts and the introduction of new technologies are great challenges. In this study, through bibliometric analysis, the research trends and hotspots on prenatal stress (PS) were explored to comprehend clinical treatments and recommend future scientific research directions.
Studies on PS published on the Web of Science Core Collection (WoSCC) database between 2011 and 2021 were reviewed. Bibliometric analysis was conducted according to the number of publications, keywords, journals, citations, affiliations, and countries. With the data collected from the WoSCC, visualization of geographic distribution; clustering analysis of keywords, affiliations, and authors; and descriptive analysis and review of PS were carried out.
A total of 7,087 articles published in 2011-2021 were retrieved. During this period, the number of publications increased. Psychoneuroendocrinology is the leading journal on PS. The largest contributor was the United States. The University of California system was leading among institutions conducting relevant research. Wang H, King S, and Tain YL were scholars with significant contributions. Hotspots were classified into four clusters, namely, pregnancy, prenatal stress, oxidative stress, and growth.
The number of studies on PS increased. Journals, countries, institutions, researchers with the most contributions, and most cited articles worldwide were extracted. Studies have mostly concentrated on treating diseases, the application of new technologies, and the analysis of epidemiological characteristics. Multidisciplinary integration is becoming the focus of current development. Epigenetics is increasingly used in studies on PS. Thus, it constitutes a solid foundation for future clinical medical and scientific research.
孕期母亲压力会增加后代患精神障碍的风险。临床概念的不断涌现和新技术的引入带来了巨大挑战。在本研究中，通过文献计量分析，探索产前压力（PS）的研究趋势和热点，以了解临床治疗情况并推荐未来的科学研究方向。
回顾了2011年至2021年期间发表在科学引文索引核心合集（WoSCC）数据库上的关于PS的研究。根据出版物数量、关键词、期刊、引文、机构隶属关系和国家进行文献计量分析。利用从WoSCC收集的数据，进行地理分布可视化；关键词、机构隶属关系和作者的聚类分析；以及对PS的描述性分析和综述。
共检索到2011 - 2021年发表的7087篇文章。在此期间，出版物数量有所增加。《心理神经内分泌学》是关于PS的领先期刊。最大贡献者是美国。加利福尼亚大学系统在开展相关研究的机构中处于领先地位。王H、金S和tain YL是有重大贡献的学者。热点被分为四个聚类，即妊娠、产前压力、氧化应激和生长。
关于PS的研究数量有所增加。提取了全球贡献最大的期刊、国家、机构、研究人员以及被引用最多的文章。研究大多集中在疾病治疗、新技术应用和流行病学特征分析上。多学科整合正成为当前发展的重点。表观遗传学在PS研究中的应用越来越多。因此，它为未来的临床医学和科学研究奠定了坚实基础。
