基于综合病例的临床方法，以理解神经退行性疾病的发病机制、复杂性、陷阱和挑战。
Integrated case-based clinical approach in understanding pathways, complexities, pitfalls and challenges in neurodegenerative disorders.
作者信息
Dhavala Aashitha, Samitinjay Aditya, Khairkar Praveen, Podder Vivek, Price Amy, Fatima Syeda Hira, Biswas Rakesh
机构信息
Junior Resident in General Medicine, Kamineni Institute of Medical Sciences Narketpally, India.
Senior Resident in General Medicine, Government General & Chest Hospital Erragada, Hyderabad, India.
出版信息
Am J Neurodegener Dis. 2022 Jun 20;11(2):22-33. eCollection 2022.
INTRODUCTION
This paper presents 5 cases of neurodegenerative disorders from our tertiary care rural hospital in south India. The purpose of this paper is to generate an emerging common theme by thematic analysis of clinical data from each of these patients. A theme emerged, we identified that there was a common clinical ground in patients with movement disorders and psychiatric symptoms. From this common theme, these patients eventually went on to develop different courses of illnesses.
METHODOLOGY
Clinical analysis of a case series of 5 patients with neurodegenerative disorders attending the Medicine or Psychiatry services of our hospital.
CONCLUSION
A clear & consistent association between movement disorders and psychiatric symptoms was found. Although our data is limited, we conclude that movement disorders can be early clinical markers of organic psychopathology. However, we are aware that this association can be confounded by substance abuse, stress, sleep disruption and even therapeutic interventions, and thus these factors were accounted for and yet we conclude that movement disorders can be early clinical indictors of organic psychopathology.
引言
本文介绍了来自印度南部我们农村三级护理医院的5例神经退行性疾病病例。本文的目的是通过对这些患者每人的临床数据进行主题分析，得出一个新出现的共同主题。一个主题出现了，我们发现患有运动障碍和精神症状的患者存在共同的临床基础。基于这个共同主题，这些患者最终发展出了不同的病程。
方法
对我院内科或精神科就诊的5例神经退行性疾病患者的病例系列进行临床分析。
结论
发现运动障碍与精神症状之间存在明确且一致的关联。尽管我们的数据有限，但我们得出结论，运动障碍可能是器质性精神病理学的早期临床标志物。然而，我们意识到这种关联可能会因药物滥用、压力、睡眠中断甚至治疗干预而混淆，因此我们考虑了这些因素，但仍得出结论，运动障碍可能是器质性精神病理学的早期临床指标。
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