Asri Nurul Ain Najihah, Mahat Mohd Muzamir, Zakaria Azlan, Safian Muhd Fauzi, Abd Hamid Umi Marshida
School of Physics and Material Studies, Faculty of Applied Sciences, Universiti Teknologi MARA, Shah Alam, Malaysia.
School of Industrial Technology, Faculty of Applied Sciences, Universiti Teknologi MARA, Shah Alam, Malaysia.
Front Bioeng Biotechnol. 2022 Jul 7;10:876696. doi: 10.3389/fbioe.2022.876696. eCollection 2022.
Conductive scaffolds, defined as scaffold systems capable of carrying electric current, have been extensively researched for tissue engineering applications. Conducting polymers (CPs) as components of conductive scaffolds was introduced to improve morphology or cell attachment, conductivity, tissue growth, and healing rate, all of which are beneficial for cardiac, muscle, nerve, and bone tissue management. Conductive scaffolds have become an alternative for tissue replacement, and repair, as well as to compensate for the global organ shortage for transplantation. Previous researchers have presented a wide range of fabrication methods for conductive scaffolds. This review highlights the most recent advances in developing conductive scaffolds, with the aim to trigger more theoretical and experimental work to address the challenges and prospects of these new fabrication techniques in medical sciences.
导电支架被定义为能够传导电流的支架系统，已被广泛研究用于组织工程应用。作为导电支架组件的导电聚合物（CPs）被引入以改善形态或细胞附着、导电性、组织生长和愈合速率，所有这些都有利于心脏、肌肉、神经和骨组织管理。导电支架已成为组织替代、修复以及弥补全球移植器官短缺的一种选择。先前的研究人员已经提出了多种导电支架的制造方法。本综述重点介绍了导电支架开发的最新进展，旨在引发更多的理论和实验工作，以应对这些新制造技术在医学科学中的挑战和前景。
