Burgess D B, Olk R J, Uniat L M
Ophthalmology. 1987 Apr;94(4):362-6. doi: 10.1016/s0161-6420(87)33438-4.
Fifty-three eyes of 31 patients over age 50 with macular disease were reviewed. Clinical appearance of the macula was of two types: a yellow slightly elevated lesion (29 eyes) and a pigmented flat lesion with surrounding atrophy (24 eyes). Drusen were found in 60% of affected eyes. No familial tendencies were documented. A reduced electro-oculogram (EOG) was present in approximately 50% of all eyes tested. Fluorescein angiographic findings and differential diagnosis are described. Visual prognosis was markedly different for the two groups: 69% of eyes with yellow elevated lesions lost two or more lines of visual acuity and 48% went on to visual acuity equal to or less than 20/200, whereas 33% of eyes with pigmented flat lesions lost two or more lines of visual acuity and 8% went on to visual acuity equal to or less than 20/200.
对31例年龄超过50岁的黄斑疾病患者的53只眼进行了回顾性研究。黄斑的临床表现有两种类型：黄色略隆起病变（29只眼）和伴有周围萎缩的色素沉着扁平病变（24只眼）。60%的患眼中发现了玻璃膜疣。未记录到家族倾向。在所有接受测试的眼中，约50%出现了眼电图（EOG）降低。描述了荧光素血管造影结果及鉴别诊断。两组的视觉预后明显不同：黄色隆起病变的眼中，69%视力下降两行或更多，48%的视力降至20/200或更低；而色素沉着扁平病变的眼中，33%视力下降两行或更多，8%的视力降至20/200或更低。
