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基于二维材料的电化学葡萄糖传感器的最新进展和未来展望。

Recent Developments and Future Perspective on Electrochemical Glucose Sensors Based on 2D Materials.

机构信息

Centre for Nano and Material Science, Jain University, Jain Global Campus, Jakkasandra, Ramanagara, Bangalore 562 112, Karnataka, India.

International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam 686 560, Kerala, India.

出版信息

Biosensors (Basel). 2022 Jun 28;12(7):467. doi: 10.3390/bios12070467.

Abstract

Diabetes is a health disorder that necessitates constant blood glucose monitoring. The industry is always interested in creating novel glucose sensor devices because of the great demand for low-cost, quick, and precise means of monitoring blood glucose levels. Electrochemical glucose sensors, among others, have been developed and are now frequently used in clinical research. Nonetheless, despite the substantial obstacles, these electrochemical glucose sensors face numerous challenges. Because of their excellent stability, vast surface area, and low cost, various types of 2D materials have been employed to produce enzymatic and nonenzymatic glucose sensing applications. This review article looks at both enzymatic and nonenzymatic glucose sensors made from 2D materials. On the other hand, we concentrated on discussing the complexities of many significant papers addressing the construction of sensors and the usage of prepared sensors so that readers might grasp the concepts underlying such devices and related detection strategies. We also discuss several tuning approaches for improving electrochemical glucose sensor performance, as well as current breakthroughs and future plans in wearable and flexible electrochemical glucose sensors based on 2D materials as well as photoelectrochemical sensors.

摘要

糖尿病是一种需要持续监测血糖的健康紊乱。由于人们对低成本、快速和精确监测血糖水平的方法有巨大的需求,因此行业一直热衷于开发新型葡萄糖传感器设备。电化学葡萄糖传感器就是其中之一,已经被开发出来,并在临床研究中经常使用。尽管面临着巨大的障碍,但这些电化学葡萄糖传感器仍面临着许多挑战。由于其优异的稳定性、巨大的表面积和低成本,各种类型的二维材料已被用于生产酶和非酶葡萄糖传感应用。本文综述了二维材料制备的酶和非酶葡萄糖传感器。另一方面,我们集中讨论了许多重要论文中涉及传感器构建和制备传感器使用的复杂性,以便读者能够理解这些器件和相关检测策略的基本概念。我们还讨论了几种用于提高电化学葡萄糖传感器性能的调谐方法,以及基于二维材料的可穿戴和柔性电化学葡萄糖传感器以及光电化学传感器的最新突破和未来计划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f985/9313175/aa192a10575e/biosensors-12-00467-g001.jpg

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