Luo Ban, Wang Wei, Li Xinyu, Zhang Hong, Zhang Yaoli, Hu Weikun
Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, China.
Department of Ophthalmology, Tianyou Hospital/Tongji Hospital, Wuhan University of Science and Technology, Wuhan 430072, China.
J Clin Med. 2022 Jul 8;11(14):3981. doi: 10.3390/jcm11143981.
The correlation between intraocular pressure (IOP) and the magnetic resonance imaging (MRI) parameters in thyroid-associated ophthalmopathy (TAO) patients was explored.
This study included 82 eyes in 41 TAO patients who had a large difference in the IOP between each eye. We measured the T2 relaxation time (T2RT) of the extraocular muscles (EOMs), the orbital fat, and the area of the EOMs.
There was a positive correlation between IOP and exophthalmos, the clinical activity score (CAS), the T2RT (of the medial rectus (MR)), the area of the MR, inferior rectus (IR) and lateral rectus, and the mean area. We established a regression model with IOP as the dependent variable, and the area of the IR was statistically significant.
High IOP in TAO patients was positively correlated with the degree of exophthalmos and EOM inflammation (especially the inferior rectus). The state of the EOMs in an orbital MRI may partially explain high IOP and provide the necessary clinical information for subsequent high IOP treatment.
探讨甲状腺相关眼病（TAO）患者眼压（IOP）与磁共振成像（MRI）参数之间的相关性。
本研究纳入41例TAO患者的82只眼，每只眼的IOP差异较大。我们测量了眼外肌（EOMs）、眶脂肪的T2弛豫时间（T2RT）以及EOMs的面积。
IOP与眼球突出度、临床活动评分（CAS）、（内直肌（MR）的）T2RT、MR、下直肌（IR）和外直肌的面积以及平均面积呈正相关。我们建立了以IOP为因变量的回归模型，IR面积具有统计学意义。
TAO患者的高IOP与眼球突出度和EOMs炎症程度（尤其是下直肌）呈正相关。眼眶MRI中EOMs的状态可能部分解释高IOP，并为后续高IOP治疗提供必要的临床信息。
