Kuebler Aylin Garip, Wiecha Caroline, Reznicek Lukas, Klingenstein Annemarie, Halfter Kathrin, Priglinger Siegfried, Hintschich Christoph
Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany.
Private Praxis Professor Lachenmayr & PD Reznicek, Munich, Germany.
Graefes Arch Clin Exp Ophthalmol. 2019 Sep;257(9):2025-2032. doi: 10.1007/s00417-019-04367-2. Epub 2019 Jun 20.
To evaluate the correlation of the intraocular pressure measurements (IOP) with non-contact tonometer Corvis Scheimpflug technology (Corvis ST), Goldmann applanation tonometry (GAT), ocular response analyzer (ORA), and iCARE rebound tonometer in patients with thyroid-associated orbitopathy (TAO) and eye-healthy subjects (control group).
Twenty-nine consecutive patients with TAO (79% female) and 30 eye-healthy subjects (60% female) were included in this prospective, age- and sex-matched study. The IOP measurement with Corvis, ORA, GAT, iCARE, and central corneal thickness (CCT) with Corvis was obtained from all study participants.
The mean age of the patients was 51 ± 10 years in patients with TAO and 56 ± 13 years in the control group. The mean IOP measurements with GAT, Corvis, ORA, and iCARE were 15.93 ± 4.42 mmHg, 18.10 ± 7.54 mmHg, 18.40 ± 7.93 mmHg, and 16.61 ± 7.96 mmHg in patients with TAO and 14.52 ± 3.02 mmHg, 14.48 ± 3.38 mmHg, 15.29 ± 4.64 mmHg, and 14.13 ± 3.85 mmHg in the control group (P = 0.157, P = 0.004, P = 0.017, and P = 0.176 respectively). The mean CCT was 547.5 ± 39.2 μm in patients with TAO and 560.8 ± 49.8 μm in the control group ( P= 0.261).
The data collected shows an agreement between the iCARE and GAT IOP measurements in TAO patients and in eye-healthy patients. However, the mean value of IOP measurements with Corvis and ORA was significantly higher in patients with TAO in comparison with the control group (P = 0.044 and P = 0.029 respectively).
评估非接触眼压计Corvis Scheimpflug技术（Corvis ST）、Goldmann压平眼压计（GAT）、眼反应分析仪（ORA）和iCARE回弹眼压计测量甲状腺相关眼病（TAO）患者及眼部健康受试者（对照组）眼压的相关性。
本前瞻性、年龄和性别匹配研究纳入了29例连续的TAO患者（79%为女性）和30例眼部健康受试者（60%为女性）。所有研究参与者均接受了Corvis、ORA、GAT、iCARE眼压测量以及Corvis测量中央角膜厚度（CCT）。
TAO患者的平均年龄为51±10岁，对照组为56±13岁。TAO患者使用GAT、Corvis、ORA和iCARE测量的平均眼压分别为15.93±4.42 mmHg、18.10±7.54 mmHg、18.40±7.93 mmHg和16.61±7.96 mmHg，对照组分别为14.52±3.02 mmHg、14.48±3.38 mmHg、15.29±4.64 mmHg和14.13±3.85 mmHg（P分别为0.157、0.004、0.017和0.176）。TAO患者的平均CCT为547.5±39.2μm，对照组为560.8± 49.8μm（P = 0.261）。
收集的数据表明，iCARE和GAT测量TAO患者及眼部健康患者眼压的结果具有一致性。然而，与对照组相比，TAO患者使用Corvis和ORA测量的眼压平均值显著更高（P分别为0.044和0.029）。
