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放射性视网膜病变合并皮质类固醇诱导性中心性浆液性脉络膜视网膜病变患者的诊断和治疗挑战。

Diagnostic and Therapeutic Challenges in a Patient with Radiation Retinopathy Complicated by Corticosteroid-Induced Central Serous Chorioretinopathy.

机构信息

Department of Ophthalmology, Clinic of Ophthalmology and Ocular Oncology, Faculty of Medicine, Jagiellonian University Medical College, 31-551 Cracow, Poland.

Dobry Wzrok Ophthalmological Clinic, 80-402 Gdańsk, Poland.

出版信息

Medicina (Kaunas). 2022 Jun 28;58(7):862. doi: 10.3390/medicina58070862.

Abstract

Central serous chorioretinopathy (CSC) is a common chorioretinal disorder. It has been postulated that impaired retinal pigment epithelium and hyperpermeability of the choriocapillaris may be involved in the development of CSC, but the exact pathomechanism has not been established. We report an unusual case of a middle-aged man who developed CSC after triamcinolone acetonide injection for macular edema. Edema developed as a late complication of radiation retinopathy after brachytherapy for childhood retinoblastoma. Steroid treatment is an important risk factor for CSC, but the underlying causative mechanisms have not been fully elucidated. It is important to increase the awareness of this link among clinicians who prescribe exogenous corticosteroids, irrespective of the route of administration.

摘要

中心性浆液性脉络膜视网膜病变(CSC)是一种常见的脉络膜视网膜疾病。有人推测,视网膜色素上皮功能障碍和脉络膜毛细血管通透性增加可能与 CSC 的发生有关,但确切的发病机制尚未确定。我们报告了一例中年男性的罕见病例,他在接受曲安奈德治疗黄斑水肿后发生 CSC。水肿是儿童视网膜母细胞瘤近距离放射治疗后放射性视网膜病变的晚期并发症。皮质类固醇治疗是 CSC 的一个重要危险因素,但潜在的致病机制尚未完全阐明。重要的是要提高开具外源性皮质类固醇药物的临床医生对此联系的认识,无论给药途径如何。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/070b/9323662/b133cb2e7f2b/medicina-58-00862-g001.jpg

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