State Key Laboratory of Aridland Crop Science, College of Agronomy, Gansu Agricultural University, Lanzhou 730070, China.
Molecules. 2022 Jul 20;27(14):4617. doi: 10.3390/molecules27144617.
The chemical components and medicinal properties of different medicinal parts of are often used as medicine after being divided into the head, body and tail of . In this study, the chemical components of different medicinal parts in different periods were analyzed by GC-MS for the first time, and the differences of the accumulation rules of chemical components in different medicinal parts of were obtained. This study demonstrated that the differences of composition accumulation in different medicinal parts of were mainly reflected in the types and relative contents of compounds. The study found that the number of compounds in different medicinal parts of in each period were different and the change rules of the same compound in different medicinal parts were also different. The number of compounds in the tail of was the least in April, and the largest in October. The content of ligustilide in the body of was higher in April and was the highest in the tail in October. The relative content of butylidenephthalide in the head was the highest in October. The relative contents of senkyunolide A and butylphthalide in the head were decreased in October, while the contents in the body and tail increased, indicating that the compounds that accumulate in the head may transfer to the body and tail in later stages of growth. This study clarified the differences in the accumulation of chemical components in different medicinal parts of , which could provide a theoretical basis for the reasons for the differences of chemical components in the different medicinal parts.
不同药用部位的化学成分和药用特性通常在被分为头、身和尾后被用于制药。在这项研究中，首次通过 GC-MS 分析了不同时期不同药用部位的化学成分，并得出了不同药用部位化学成分积累规律的差异。本研究表明，不同药用部位化学成分的组成积累差异主要体现在化合物的种类和相对含量上。研究发现，不同时期的不同药用部位的化合物数量不同，同一化合物在不同药用部位的变化规律也不同。4 月时， 的尾部的化合物数量最少，10 月时最多。4 月时， 的身部的藁本内酯含量较高，10 月时在尾部的含量最高。10 月时， 的头部的丁烯基苯酞的相对含量最高。10 月时， 的头部的川芎嗪 A 和丁基苯酞的相对含量降低，而在身部和尾部的含量增加，这表明在生长后期，积累在头部的化合物可能转移到身部和尾部。本研究阐明了不同药用部位化学成分积累的差异，可为不同药用部位化学成分差异的原因提供理论依据。
