Beijing University of Chinese Medicine, Beijing 100029, China.
Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing 100029, China.
Nutrients. 2022 Jul 11;14(14):2841. doi: 10.3390/nu14142841.
We examined 3962 people aged 20 to 49 years who had information on spirometry testing and underwent a 24 h dietary recall interview from the 2007-2012 National Health and Nutrition Examination Survey (NHANES) and used multivariable logistic regression to evaluate associations between Dietary Inflammatory Index (DII, a pro-inflammatory diet) and early COPD and lung function. The overall prevalence of early COPD was 5.05%. Higher DII was associated with increased odds of early COPD (quartile 4 vs. 1, the OR = 1.657, 95% CI = 1.100-2.496, = 0.0156). In a full-adjusted model, each unit of increase in DII score was associated with a 90.3% increase in the risk of early COPD. Higher DII is significantly associated with lower FEV and FVC among individuals with early COPD, each unit increment in the DII was significantly associated with 0.43 L-0.58 L decrements in FEV (β = -0.43, 95% CI = -0.74, -0.12) and FVC (β = -0.58, 95% CI = -1.01, -0.16). These findings demonstrate that higher consumption of a pro-inflammatory diet may contribute to an increased risk of early COPD and lower lung function, and further support dietary interventions as part of a healthy lifestyle in order to preserve lung function and prevent or improve COPD.
我们研究了 3962 名 20 至 49 岁的成年人，这些人有肺量测定检测信息，并接受了 2007-2012 年全国健康和营养检查调查（NHANES）的 24 小时饮食回忆访谈。我们使用多变量逻辑回归评估饮食炎症指数（DII，促炎饮食）与早期 COPD 和肺功能之间的关联。早期 COPD 的总体患病率为 5.05%。较高的 DII 与早期 COPD 的患病几率增加相关（四分位 4 与 1 相比，OR = 1.657，95%CI = 1.100-2.496，P = 0.0156）。在完全调整的模型中，DII 评分每增加一个单位，早期 COPD 的患病风险就会增加 90.3%。较高的 DII 与早期 COPD 患者的 FEV 和 FVC 显著降低相关，DII 每增加一个单位，FEV 就会显著降低 0.43-0.58L（β = -0.43，95%CI = -0.74，-0.12），FVC 也会显著降低 0.58-1.01L（β = -0.58，95%CI = -1.01，-0.16）。这些发现表明，促炎饮食的摄入增加可能会导致早期 COPD 的患病风险增加和肺功能下降，进一步支持将饮食干预作为健康生活方式的一部分，以保护肺功能，预防或改善 COPD。
