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患有单一或多种心脏代谢疾病的绝经后女性的氧化还原状态对普拉提垫上训练有相似的反应。

Redox Status of Postmenopausal Women with Single or Multiple Cardiometabolic Diseases Has a Similar Response to Mat Pilates Training.

作者信息

Amaral Ana Luiza, Batista Jaqueline Pontes, Mariano Igor Moraes, Gonçalves Ludimila Ferreira, Tavares Júlia Buiatte, de Souza Adriele Vieira, Caixeta Douglas C, Teixeira Renata R, de Oliveira Erick P, Espindola Foued S, Puga Guilherme Morais

机构信息

Laboratory of Cardiorespiratory and Metabolic Physiology, Federal University of Uberlândia, Uberlândia 38400-678, Minas Gerais, Brazil.

Laboratory of Biochemistry and Molecular Biology, Institute of Biotechnology, Federal University of Uberlândia, Uberlândia 38400-902, Minas Gerais, Brazil.

出版信息

Antioxidants (Basel). 2022 Jul 26;11(8):1445. doi: 10.3390/antiox11081445.

Abstract

Postmenopausal women have a high prevalence of cardiometabolic diseases and that may associate with higher oxidative stress. Exercise can contribute to the treatment of such diseases, but some modalities, such as Mat Pilates, need to be further studied in terms of their physiological responses. Our aim was to investigate the effects of 12 weeks of Mat Pilates on redox status in postmenopausal women with one or multiple comorbidities of cardiometabolic diseases. Forty-four postmenopausal women were divided into two groups: SINGLE, composed of women with one cardiometabolic disease ( = 20) and MULT, with multimorbidity ( = 24). Mat Pilates training was conducted three times a week for 12 weeks, and each session lasted 50 min. Plasma samples were collected before and after training to analyze the following redox markers: superoxide dismutase, catalase, glutathione peroxidase, total antioxidant capacity due to ferric-reducing antioxidant power (FRAP), reduced glutathione (GSH), uric acid, and carbonyl protein. ANCOVA showed interaction effects in FRAP ( = 0.014). Both groups had reduced levels of catalase ( = 0.240) and GSH ( = 0.309), and increased levels of carbonyl protein ( = 0.053) after intervention. In conclusion, the redox status of postmenopausal women shows no changes mediated by Mat Pilates training between SINGLE and MULT, except for greater reductions of FRAP in SINGLE.

摘要

绝经后女性心血管代谢疾病的患病率较高,这可能与较高的氧化应激有关。运动有助于此类疾病的治疗,但某些运动方式,如垫上普拉提,在生理反应方面仍需进一步研究。我们的目的是调查为期12周的垫上普拉提对患有一种或多种心血管代谢疾病合并症的绝经后女性氧化还原状态的影响。44名绝经后女性被分为两组:SINGLE组,由患有一种心血管代谢疾病的女性组成(n = 20);MULT组,患有多种合并症(n = 24)。垫上普拉提训练每周进行3次,共12周,每次训练持续50分钟。在训练前后采集血浆样本,以分析以下氧化还原标志物:超氧化物歧化酶、过氧化氢酶、谷胱甘肽过氧化物酶、基于铁还原抗氧化能力(FRAP)的总抗氧化能力、还原型谷胱甘肽(GSH)、尿酸和羰基蛋白。协方差分析显示FRAP存在交互作用(P = 0.014)。干预后,两组的过氧化氢酶水平(P = 0.240)和GSH水平(P = 0.309)均降低,羰基蛋白水平升高(P = 0.053)。总之,除了SINGLE组的FRAP降低幅度更大外,垫上普拉提训练在SINGLE组和MULT组之间并未介导绝经后女性氧化还原状态的变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1f0/9331979/e45a24300bd8/antioxidants-11-01445-g001.jpg

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