Preprocedural Mouthwashes for Reduction of SARS-CoV-2 Viral Load and Infectivity.
作者信息
Cieplik F, Jakubovics N S
机构信息
Department of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.
School of Dental Sciences, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
出版信息
J Dent Res. 2022 Nov;101(12):1421-1423. doi: 10.1177/00220345221110444. Epub 2022 Jul 27.
Abstract
摘要
相似文献
1
Preprocedural Mouthwashes for Reduction of SARS-CoV-2 Viral Load and Infectivity.用于降低SARS-CoV-2病毒载量和传染性的术前漱口水。
J Dent Res. 2022 Nov;101(12):1421-1423. doi: 10.1177/00220345221110444. Epub 2022 Jul 27.
2
Efficacy of a Mouthwash Containing CHX and CPC in SARS-CoV-2-Positive Patients: A Randomized Controlled Clinical Trial.含 CHX 和 CPC 的漱口液对 SARS-CoV-2 阳性患者的疗效：一项随机对照临床试验。
J Dent Res. 2023 Jun;102(6):608-615. doi: 10.1177/00220345231156415. Epub 2023 Mar 21.
3
Preprocedural mouthwashes for infection control in dentistry-an update.口腔预处理漱口水在牙科感染控制中的应用——更新。
Clin Oral Investig. 2023 Jun;27(Suppl 1):33-44. doi: 10.1007/s00784-023-04953-z. Epub 2023 Apr 20.
4
Effect of oral antiseptics in reducing SARS-CoV-2 infectivity: evidence from a randomized double-blind clinical trial.口腔抗菌剂对降低 SARS-CoV-2 感染力的效果：一项随机、双盲临床试验的证据。
Emerg Microbes Infect. 2022 Dec;11(1):1833-1842. doi: 10.1080/22221751.2022.2098059.
5
Oral mouthwashes for asymptomatic to mildly symptomatic adults with COVID-19 and salivary viral load: a randomized, placebo-controlled, open-label clinical trial.用于 COVID-19 无症状或轻度症状成人的口腔漱口液与唾液病毒载量：一项随机、安慰剂对照、开放标签临床试验。
BMC Oral Health. 2024 Apr 25;24(1):491. doi: 10.1186/s12903-024-04246-1.
6
Effect of phthalocyanine oral and nasal antiseptic solutions on the infectivity of SARS-CoV-2 in patients with COVID-19: a randomized controlled trial.新型冠状病毒肺炎患者经口及鼻腔用酞菁口腔抗菌溶液对 SARS-CoV-2 感染力的影响：一项随机对照试验。
Ger Med Sci. 2023 Jun 23;21:Doc07. doi: 10.3205/000321. eCollection 2023.
7
Effectiveness of mouthwashes on reducing SARS-CoV-2 viral load in oral cavity: a systematic review and meta-analysis.含漱剂对减少口腔 SARS-CoV-2 病毒载量的有效性：系统评价和荟萃分析。
BMC Oral Health. 2023 Jul 3;23(1):443. doi: 10.1186/s12903-023-03126-4.
8
A critical appraisal of evidence in the use of preprocedural mouthwash to avoid SARS-CoV-2 transmission during oral interventions.对术前使用漱口水以避免在口腔干预期间传播严重急性呼吸综合征冠状病毒2的证据进行的批判性评估。
Eur Rev Med Pharmacol Sci. 2020 Oct;24(19):10222-10224. doi: 10.26355/eurrev_202010_23245.
9
Efficacy of Cetylpyridinium Chloride mouthwash against SARS-CoV-2: A systematic review of randomized controlled trials.聚维酮碘含漱液抗 SARS-CoV-2 的疗效：一项随机对照试验的系统评价。
Mol Oral Microbiol. 2023 Jun;38(3):171-180. doi: 10.1111/omi.12408. Epub 2023 Mar 3.
10
Reducing the viral load of SARS-CoV-2 in the saliva of patients with COVID-19.降低 COVID-19 患者唾液中 SARS-CoV-2 的病毒载量。
Oral Dis. 2022 Nov;28 Suppl 2:2474-2480. doi: 10.1111/odi.14118. Epub 2022 Jan 6.
引用本文的文献
1
Antiseptics as effective virucidal agents against SARS-CoV-2: Systematic review and Bayesian network meta-analysis.作为对抗新型冠状病毒有效杀病毒剂的防腐剂：系统评价与贝叶斯网络荟萃分析
Jpn Dent Sci Rev. 2025 Dec;61:138-154. doi: 10.1016/j.jdsr.2025.05.001. Epub 2025 Jun 10.
2
A Cetylpyridinium Chloride Oral Rinse Reduces Salivary Viral Load in Randomized Controlled Trials.在随机对照试验中，氯化十六烷基吡啶口服含漱液可降低唾液病毒载量。
JDR Clin Trans Res. 2024 Dec 9;10(4):23800844241296840. doi: 10.1177/23800844241296840.
3
Effectiveness of Preprocedural Mouthwashes: A Triple-Blind Randomised Controlled Clinical Trial.术前漱口水的有效性：一项三盲随机对照临床试验。
Int Dent J. 2025 Apr;75(2):868-876. doi: 10.1016/j.identj.2024.08.017. Epub 2024 Oct 6.
4
Optimal effective concentration combinations (OPECCs) for binary application of membrane-targeting antiseptics and TMPyP-mediated antimicrobial photodynamic therapy.优化有效浓度组合（OPECCs）在膜靶向防腐剂的二元应用和 TMPyP 介导的抗菌光动力疗法中的应用。
Photochem Photobiol Sci. 2024 Jan;23(1):189-196. doi: 10.1007/s43630-023-00512-3. Epub 2023 Dec 19.
5
Mouthwash Effects on the Oral Microbiome: Are They Good, Bad, or Balanced?漱口水对口腔微生物组的影响：是好是坏还是平衡？
Int Dent J. 2023 Nov;73 Suppl 2(Suppl 2):S74-S81. doi: 10.1016/j.identj.2023.08.010. Epub 2023 Oct 17.
6
Preprocedural mouthwashes for infection control in dentistry-an update.口腔预处理漱口水在牙科感染控制中的应用——更新。
Clin Oral Investig. 2023 Jun;27(Suppl 1):33-44. doi: 10.1007/s00784-023-04953-z. Epub 2023 Apr 20.
7
effect of mouthwashes on viable viral load of SARS-CoV-2 in saliva: a pilot study.漱口水对唾液中新冠病毒活病毒载量的影响：一项初步研究。
J Oral Microbiol. 2023 Apr 11;15(1):2198432. doi: 10.1080/20002297.2023.2198432. eCollection 2023.
本文引用的文献
1
Ecological Effects of Daily Antiseptic Treatment on Microbial Composition of Saliva-Grown Microcosm Biofilms and Selection of Resistant Phenotypes.每日使用抗菌剂对唾液培养的微生态生物膜微生物组成及耐药表型选择的生态效应
Front Microbiol. 2022 Jun 30;13:934525. doi: 10.3389/fmicb.2022.934525. eCollection 2022.
2
Cetylpyridinium Chloride Mouthwash to Reduce Shedding of Infectious SARS-CoV-2: A Double-Blind Randomized Clinical Trial.十六烷基氯化吡啶漱口水可减少传染性严重急性呼吸综合征冠状病毒2的脱落：一项双盲随机临床试验。
J Dent Res. 2022 Nov;101(12):1450-1456. doi: 10.1177/00220345221102310. Epub 2022 Jun 21.
3
Mouthrinses against SARS-CoV-2 - High antiviral effectivity by membrane disruption in vitro translates to mild effects in a randomized placebo-controlled clinical trial.含漱剂抗 SARS-CoV-2-体外通过破坏细胞膜实现高抗病毒效果，在随机安慰剂对照临床试验中效果轻微。
Virus Res. 2022 Jul 15;316:198791. doi: 10.1016/j.virusres.2022.198791. Epub 2022 May 2.
4
CPC-containing oral rinses inactivate SARS-CoV-2 variants and are active in the presence of human saliva.含 CPC 的漱口液可使 SARS-CoV-2 变异株失活，并在存在人唾液的情况下仍保持活性。
J Med Microbiol. 2022 Feb;71(2). doi: 10.1099/jmm.0.001508.
5
Cetylpyridinium chloride promotes disaggregation of SARS-CoV-2 virus-like particles.十六烷基氯化吡啶促进严重急性呼吸综合征冠状病毒2（SARS-CoV-2）病毒样颗粒的解聚。
J Oral Microbiol. 2022 Jan 24;14(1):2030094. doi: 10.1080/20002297.2022.2030094. eCollection 2022.
6
Clinical evaluation of antiseptic mouth rinses to reduce salivary load of SARS-CoV-2.临床评价抗菌漱口液对减少 SARS-CoV-2 唾液负荷的作用。
Sci Rep. 2021 Dec 22;11(1):24392. doi: 10.1038/s41598-021-03461-y.
7
Estimating salivary carriage of severe acute respiratory syndrome coronavirus 2 in nonsymptomatic people and efficacy of mouthrinse in reducing viral load: A randomized controlled trial.估算无症状人群中严重急性呼吸综合征冠状病毒 2 的唾液携带情况以及漱口液降低病毒载量的效果：一项随机对照试验。
J Am Dent Assoc. 2021 Nov;152(11):903-908. doi: 10.1016/j.adaj.2021.05.021. Epub 2021 Jun 11.
8
Mouthwashes with CPC Reduce the Infectivity of SARS-CoV-2 Variants In Vitro.含 CPC 的漱口水可降低 SARS-CoV-2 变异株的体外传染性。
J Dent Res. 2021 Oct;100(11):1265-1272. doi: 10.1177/00220345211029269. Epub 2021 Jul 20.
9
Use of chlorhexidine to eradicate oropharyngeal SARS-CoV-2 in COVID-19 patients.使用洗必泰清除 COVID-19 患者口咽部的 SARS-CoV-2。
J Med Virol. 2021 Jul;93(7):4370-4373. doi: 10.1002/jmv.26954. Epub 2021 Apr 1.
10
Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Nasopharyngeal Viral Load in Patients With COVID-19: A Randomized Clinical Trial.聚维酮碘漱口液、含漱液和鼻腔喷雾剂降低 COVID-19 患者鼻咽部病毒载量的随机临床试验。
JAMA Otolaryngol Head Neck Surg. 2021 Apr 1;147(4):400-401. doi: 10.1001/jamaoto.2020.5490.
Zotero 插件