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酚类化合物在 物种中的存在及其在炎症过程中的作用:综述。

Phenolic Compounds' Occurrence in Species and Their Role in the Inflammatory Process: A Review.

机构信息

Laboratoire de Biochimie Appliquée, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, Bejaia 06000, Algeria.

CIIMAR-Interdisciplinary Centre of Marine and Environmental Research, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos s/n, 4450-208 Matosinhos, Portugal.

出版信息

Molecules. 2022 Jul 25;27(15):4763. doi: 10.3390/molecules27154763.

Abstract

Within the family, comprises the most widespread species, with a recognized importance in human life, including feeding, domestic use as home natural barriers, and as a traditional remedy for diverse diseases and conditions such asthma, edema, and burns. Indeed, scientific reports have stated that these health benefits may be due to various active compounds, particularly polyphenols, which are ubiquitously found in plants and have proven their pharmacological efficiency by displaying antimicrobial, anti-cancer, and anti-inflammatory activities, among others. species contain different classes of phenolic compounds that are recognized for their anti-inflammatory potential. Among them, quercetin, isorhamnetin, and kaempferol derivates were reported to greatly contribute to modulate cells' infiltration and secretion of soluble inflammatory mediators, with key implications in the inflammatory process. In this review, we make a summary of the different classes of phenolic compounds reported in species so far and explore their implications in the inflammatory process, reported by in vitro and in vivo bioassays, supporting the use of cactus in folk medicine and valorizing them from the socio-economic point of view.

摘要

在仙人掌科中,包含了分布最广泛的物种,这些物种在人类生活中具有重要作用,包括提供食物、作为家庭天然屏障的用途、以及作为治疗各种疾病和病症的传统药物,如哮喘、水肿和烧伤。事实上,科学报告表明,这些健康益处可能归因于各种活性化合物,特别是多酚,这些多酚广泛存在于植物中,并通过显示抗菌、抗癌和抗炎等活性证明了其药理学效率。仙人掌属植物包含不同类别的酚类化合物,这些化合物因其抗炎潜力而被认可。其中,槲皮素、山奈酚和山柰酚衍生物被报道能极大地调节细胞浸润和可溶性炎症介质的分泌,对炎症过程有重要影响。在这篇综述中,我们总结了迄今为止在仙人掌属植物中报道的不同类别的酚类化合物,并探讨了它们在体外和体内生物测定中报告的炎症过程中的意义,支持了仙人掌在民间医学中的应用,并从社会经济的角度对其进行了重视。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73f2/9330797/e4728310e3bc/molecules-27-04763-g001.jpg

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