Department of Community Health and Social Medicine, CUNY School of Medicine, New York, New York, United States of America.
Department of Public Health, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.
PLoS One. 2022 Jul 28;17(7):e0272252. doi: 10.1371/journal.pone.0272252. eCollection 2022.
The effects of the COVID-19 pandemic caused considerable psychological and physical effects in healthy and diseased New Yorkers aside from the effects in those who were infected. We investigated the relationship between known risk-enhancing and health-promoting factors (social and medical), comorbidity indicators, and, as the primary outcome, health-related quality of life (HRQoL).
Between April 22 and May 5, 2020, a market research agency (Dynata) administered a digital survey including the EQ-5D-5L and items related to individual characteristics, social position, occupational and insurance status, living situation, exposures (smoking and COVID-19), detailed chronic conditions, and experienced access to care to an existing internet panel representative of New Yorkers.
2684 persons completed the questionnaire. The median age was 48 years old, and most respondents were non-Hispanic white (74%) and reported at least higher vocational training or a university education (83%). During COVID-19, mean HRQoL scores were 0.82 for the EQ-5D-5L index and 79.3 for the EQ VAS. Scores varied for healthy and diseased respondents differently by the above determinants. Lower age, impaired occupational status, loss of health insurance, and limited access to care exerted more influence on EQ-5D-5L scores of diseased persons compared to healthy persons. Among diseased persons, the number of chronic conditions and limited access to health care had the strongest association with EQ-5D-5L scores. While EQ-5D-5L scores improved with increasing age, gender had no noticeable effect. Deprivation factors showed moderate effects, which largely disappeared in (stratified) multivariable analysis, suggesting mediation through excess chronic morbidity and poor healthcare access. Generally, modifying effects were larger in the EQ-5D-5L as compared to the EQ VAS.
Almost all factors relating to a disadvantaged position showed a negative association with HRQoL. In diseased respondents, pre-existing chronic comorbidity and experienced access to health care are key factors.
除了感染 COVID-19 的人之外,新冠疫情对健康和患病的纽约人造成了相当大的心理和生理影响。我们研究了已知的增强风险和促进健康的因素(社会和医疗)、合并症指标,以及作为主要结果的健康相关生活质量(HRQoL)之间的关系。
在 2020 年 4 月 22 日至 5 月 5 日期间,一家市场研究机构(Dynata)通过数字调查的方式向现有的互联网纽约人代表小组提供了一份包含 EQ-5D-5L 和与个人特征、社会地位、职业和保险状况、生活状况、接触(吸烟和 COVID-19)、详细的慢性疾病以及经历的医疗服务相关的项目。
2684 人完成了问卷调查。中位数年龄为 48 岁,大多数受访者是非西班牙裔白人(74%),并报告至少接受过高等职业培训或大学教育(83%)。在 COVID-19 期间,EQ-5D-5L 指数的平均 HRQoL 评分为 0.82,EQ VAS 评分为 79.3。健康和患病的受访者根据上述决定因素的不同,对健康相关生活质量的评分也不同。年龄较小、职业状况受损、失去健康保险和获得医疗保健的机会有限,对患病者的 EQ-5D-5L 评分的影响大于对健康者的影响。在患病者中,慢性疾病的数量和有限的医疗保健机会与 EQ-5D-5L 评分的关联最强。随着年龄的增长,EQ-5D-5L 评分有所提高,而性别则没有明显影响。贫困因素的影响较大,但在(分层)多变量分析中,这些影响大多消失,表明通过过度的慢性发病率和较差的医疗保健机会进行了中介。一般来说,在 EQ-5D-5L 中,调整效果大于 EQ VAS。
几乎所有与不利地位相关的因素都与 HRQoL 呈负相关。在患病者中,预先存在的慢性合并症和获得医疗保健的机会是关键因素。