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急性支气管炎患者的抗生素管理:一例多西环素所致食管炎的病例报告

Antibiotic Stewardship in Patients With Acute Bronchitis: A Case Report of Doxycycline-Induced Esophagitis.

作者信息

Butt Muhammad Ali, Peicher Mark, Nguyen Anthony P, Sheikh Abu Baker

机构信息

Internal Medicine, Allegheny Health Network, Pittsburgh, USA.

Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, USA.

出版信息

Cureus. 2022 Jun 26;14(6):e26354. doi: 10.7759/cureus.26354. eCollection 2022 Jun.

DOI:10.7759/cureus.26354
PMID:35903577
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9325943/
Abstract

Acute bronchitis is a self-limiting disease, characterized by mild constitutional symptoms and a cough lasting two to three weeks. The disease usually occurs secondary to viruses; therefore, only symptomatic and supportive care is advised for the patients. Despite the recommended guidelines, most patients are prescribed antibiotics. Here, we present a case of a 38-year-old female who presented to the hospital with a sudden onset of severe epigastric pain. The patient recently started a 10-day course of doxycycline for acute bronchitis. She was admitted, evaluated, and diagnosed with doxycycline-induced esophagitis, and managed accordingly. This report highlights how excessive use of antibiotics is leading to adverse effects, antibiotic resistance, increased health care costs, and invasive testing. It also emphasizes the importance of antibiotic stewardship.

摘要

急性支气管炎是一种自限性疾病,其特征为轻度全身症状和持续两到三周的咳嗽。该疾病通常继发于病毒感染;因此,建议仅对患者进行对症和支持治疗。尽管有推荐指南,但大多数患者仍被开具抗生素。在此,我们报告一例38岁女性患者,她因突发严重上腹部疼痛入院。该患者最近因急性支气管炎开始了为期10天的强力霉素治疗。她入院后接受评估,被诊断为强力霉素诱发的食管炎,并据此进行了治疗。本报告强调了过度使用抗生素如何导致不良反应、抗生素耐药性、医疗费用增加以及侵入性检查。它还强调了抗生素管理的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63eb/9325943/835fe7b59182/cureus-0014-00000026354-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63eb/9325943/e9ce73724070/cureus-0014-00000026354-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63eb/9325943/835fe7b59182/cureus-0014-00000026354-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63eb/9325943/e9ce73724070/cureus-0014-00000026354-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63eb/9325943/835fe7b59182/cureus-0014-00000026354-i02.jpg

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本文引用的文献

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Antimicrobial stewardship and antibiograms: importance of moving beyond traditional antibiograms.抗菌药物管理与抗菌谱:超越传统抗菌谱的重要性
Ther Adv Infect Dis. 2021 May 5;8:20499361211011373. doi: 10.1177/20499361211011373. eCollection 2021 Jan-Dec.
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Outpatient prescribing pattern for acute bronchitis in primary healthcare settings in China.中国基层医疗保健环境中急性支气管炎的门诊处方模式。
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《重症加强治疗病房抗生素管理实践原则》。
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